A conceptual framework for early life determinants of future multimorbidity
A conceptual framework for early life determinants of future multimorbidity
Background: social, biological and environmental factors in early life, defined as the period from preconception until age 18, play a role in shaping the risk of Multiple Long-Term Condition Multimorbidity (MLTC-M). There is a need for conceptual framing of these factors to inform and shape future research on aetiology and for modelling prevention scenarios of MLTC-M. We developed a conceptual framework to characterise early life determinants of future MLTC-M risk.
Methods: the conceptualisation of determinant domains was shaped by reviewing existing research evidence and policy, and co-produced with public contributors living in the UK via two workshops, one with 8 contributors age 18-30 regardless of MLTC-M status, and one with 12 contributors age 40-65 who all self-reported MLTC-M.
Results: domains included: 1.Prenatal, antenatal, neonatal and birth; 2.Adverse childhood experiences; 3.Child health, check-ups and screening; 4.Developmental attributes; 5.Child education and health literacy; 6.Demographics; 7. Parent health and health behaviours; 8.Socioeconomics; 9.Parental family factors; 10.Neighbourhood, physical environment and health care systems; 11.Health behaviours and diet; 12.Religion, spirituality and culture. Some domains identified by the public contributors, such as religion, health screening, check-ups, and diet, were not well represented within the research evidence or policy documents.
Conclusions: this co-produced conceptualisation can inform research to investigate the early life characteristics of population groups at risk of future MLTC-M, as well as policy directions towards prevention of early-onset MLTC-M. Additionally, it can shape the direction of further data collection, particularly with respect to the understudied domains identified by our public contributors.
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Stannard, S.
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Berrington, A.
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Paranjothy, S.
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Owen, R.
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Fraser, S.D.S.
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Hoyle, R.B.
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Batchelor, S.
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Welch, J.
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Alwan, N.A.
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24 October 2023
Stannard, S.
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Berrington, A.
bd0fc093-310d-4236-8126-ca0c7eb9ddde
Paranjothy, S.
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Owen, R.
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Fraser, S.D.S.
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Hoyle, R.B.
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Batchelor, S.
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Welch, J.
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Alwan, N.A.
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Stannard, S., Berrington, A., Paranjothy, S., Owen, R., Fraser, S.D.S., Hoyle, R.B., Batchelor, S., Welch, J. and Alwan, N.A.
(2023)
A conceptual framework for early life determinants of future multimorbidity.
European Journal of Public Health, 33 (Supplement_2), .
(doi:10.1093/eurpub/ckad160.1254).
Record type:
Meeting abstract
Abstract
Background: social, biological and environmental factors in early life, defined as the period from preconception until age 18, play a role in shaping the risk of Multiple Long-Term Condition Multimorbidity (MLTC-M). There is a need for conceptual framing of these factors to inform and shape future research on aetiology and for modelling prevention scenarios of MLTC-M. We developed a conceptual framework to characterise early life determinants of future MLTC-M risk.
Methods: the conceptualisation of determinant domains was shaped by reviewing existing research evidence and policy, and co-produced with public contributors living in the UK via two workshops, one with 8 contributors age 18-30 regardless of MLTC-M status, and one with 12 contributors age 40-65 who all self-reported MLTC-M.
Results: domains included: 1.Prenatal, antenatal, neonatal and birth; 2.Adverse childhood experiences; 3.Child health, check-ups and screening; 4.Developmental attributes; 5.Child education and health literacy; 6.Demographics; 7. Parent health and health behaviours; 8.Socioeconomics; 9.Parental family factors; 10.Neighbourhood, physical environment and health care systems; 11.Health behaviours and diet; 12.Religion, spirituality and culture. Some domains identified by the public contributors, such as religion, health screening, check-ups, and diet, were not well represented within the research evidence or policy documents.
Conclusions: this co-produced conceptualisation can inform research to investigate the early life characteristics of population groups at risk of future MLTC-M, as well as policy directions towards prevention of early-onset MLTC-M. Additionally, it can shape the direction of further data collection, particularly with respect to the understudied domains identified by our public contributors.
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ckad160.1254
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Published date: 24 October 2023
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Local EPrints ID: 485503
URI: http://eprints.soton.ac.uk/id/eprint/485503
ISSN: 1101-1262
PURE UUID: af8162c6-f238-4085-bd2e-663779421729
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Date deposited: 07 Dec 2023 17:37
Last modified: 18 Mar 2024 03:32
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Author:
S. Stannard
Author:
S. Paranjothy
Author:
R. Owen
Author:
S. Batchelor
Author:
J. Welch
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