Gene therapy access: global challenges, opportunities, and views from Brazil, South Africa, and India
Gene therapy access: global challenges, opportunities, and views from Brazil, South Africa, and India
Gene and cell therapies for a variety of life-limiting illnesses are under investigation, and a small number of commercial products have successfully obtained regulatory approval. The cost of treatment is high, and clinical studies evaluating safety and efficacy are performed predominately in high-income countries. We reviewed the current status of gene and cell therapies in low- and middle-income countries and highlighted the need and current barriers to access. The state of product development in Brazil, South Africa, and India is discussed, including lessons learned from American Society of Gene and Cell Therapy (ASGCT)-sponsored virtual symposia in each of these countries.
2122-2129
Cornetta, Kenneth
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Bonamino, Martín
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Mahlangu, Johnny
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Mingozzi, Federico
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Rangarajan, Savita
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Rao, Jayandharan
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1 June 2022
Cornetta, Kenneth
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Bonamino, Martín
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Mahlangu, Johnny
d9dbd61a-b94a-4fbc-812d-55c6434fbc09
Mingozzi, Federico
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Rangarajan, Savita
9a5e4c7e-55ba-4a3a-b5f6-f1e269d927c3
Rao, Jayandharan
bed8f1d9-b298-437e-b127-902d378c1eca
Cornetta, Kenneth, Bonamino, Martín, Mahlangu, Johnny, Mingozzi, Federico, Rangarajan, Savita and Rao, Jayandharan
(2022)
Gene therapy access: global challenges, opportunities, and views from Brazil, South Africa, and India.
Molecular Therapy, 30 (6), .
(doi:10.1016/j.ymthe.2022.04.002).
Abstract
Gene and cell therapies for a variety of life-limiting illnesses are under investigation, and a small number of commercial products have successfully obtained regulatory approval. The cost of treatment is high, and clinical studies evaluating safety and efficacy are performed predominately in high-income countries. We reviewed the current status of gene and cell therapies in low- and middle-income countries and highlighted the need and current barriers to access. The state of product development in Brazil, South Africa, and India is discussed, including lessons learned from American Society of Gene and Cell Therapy (ASGCT)-sponsored virtual symposia in each of these countries.
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e-pub ahead of print date: 4 April 2022
Published date: 1 June 2022
Identifiers
Local EPrints ID: 485956
URI: http://eprints.soton.ac.uk/id/eprint/485956
ISSN: 1525-0016
PURE UUID: c4dd65db-7ed2-43be-b6ac-149cdc757d22
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Date deposited: 04 Jan 2024 06:00
Last modified: 18 Mar 2024 03:57
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Contributors
Author:
Kenneth Cornetta
Author:
Martín Bonamino
Author:
Johnny Mahlangu
Author:
Federico Mingozzi
Author:
Jayandharan Rao
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