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Self-assembly of vesicle nanoarrays on Si: a potential new route to high-density functional protein arrays

Self-assembly of vesicle nanoarrays on Si: a potential new route to high-density functional protein arrays
Self-assembly of vesicle nanoarrays on Si: a potential new route to high-density functional protein arrays
The authors show that 100 nm unilamellar thiol-tagged vesicles bind discretely and specifically to Au nanodots formed on a Si surface. An array of such dots, consisting of 20 nm Au–Si three-dimensional islands, is formed by self-assembly on terraces of small-angle-miscut Si111 after Au deposition. Consequently, both the formation of the nanopattern and the subsequent attachment of the vesicles are self-organized and occur without the need for any “top-down” lithographic processes. This approach has the potential to provide the basis of a low-cost, high-density nanoarray for use in proteomics and drug discovery.
0003-6951
033901-033903
Ramanujan, C.S.
13c93249-ae9d-43c9-a3f6-9eb37ca6ddbe
Sumitomo, K.
1717aafa-e251-4f57-ba72-2745e41776ad
de Planque, M.R.R.
a1d33d13-f516-44fb-8d2c-c51d18bc21ba
Hibino, H.
96121a21-55fc-411b-8811-100779123972
Torimitsu, K.
4844508a-51e4-4f60-8bcb-f309b02615a0
Ryan, J.F.
2c388137-99a9-4d73-b237-31a5eaa7f692
Ramanujan, C.S.
13c93249-ae9d-43c9-a3f6-9eb37ca6ddbe
Sumitomo, K.
1717aafa-e251-4f57-ba72-2745e41776ad
de Planque, M.R.R.
a1d33d13-f516-44fb-8d2c-c51d18bc21ba
Hibino, H.
96121a21-55fc-411b-8811-100779123972
Torimitsu, K.
4844508a-51e4-4f60-8bcb-f309b02615a0
Ryan, J.F.
2c388137-99a9-4d73-b237-31a5eaa7f692

Ramanujan, C.S., Sumitomo, K., de Planque, M.R.R., Hibino, H., Torimitsu, K. and Ryan, J.F. (2007) Self-assembly of vesicle nanoarrays on Si: a potential new route to high-density functional protein arrays. Applied Physics Letters, 90 (3), 033901-033903. (doi:10.1063/1.2431774).

Record type: Article

Abstract

The authors show that 100 nm unilamellar thiol-tagged vesicles bind discretely and specifically to Au nanodots formed on a Si surface. An array of such dots, consisting of 20 nm Au–Si three-dimensional islands, is formed by self-assembly on terraces of small-angle-miscut Si111 after Au deposition. Consequently, both the formation of the nanopattern and the subsequent attachment of the vesicles are self-organized and occur without the need for any “top-down” lithographic processes. This approach has the potential to provide the basis of a low-cost, high-density nanoarray for use in proteomics and drug discovery.

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More information

Published date: 15 January 2007

Identifiers

Local EPrints ID: 48606
URI: https://eprints.soton.ac.uk/id/eprint/48606
ISSN: 0003-6951
PURE UUID: 4be0d233-df63-4f62-8acf-4557aa0df40b
ORCID for M.R.R. de Planque: ORCID iD orcid.org/0000-0002-8787-0513

Catalogue record

Date deposited: 03 Oct 2007
Last modified: 20 Jul 2019 00:51

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