Estimated radiation doses to different organs among patients treated for ankylosing spondylitis with a single course of X rays
Estimated radiation doses to different organs among patients treated for ankylosing spondylitis with a single course of X rays
A follow-up study of over 14000 patients treated with a single course of X rays for ankylosing spondylitis demonstrated a substantial excess risk of developing cancer. Previously the excess risk of leukaemia has been related to the estimated mean radiation dose to the active bone marrow but detailed estimates were not made of the radiation doses to other organs. In the present work, data extracted from the original treatment records of a random sample of one in 15 patients have been used to make dose estimates, using Monte Carlo methods, for 30 specific organs or regions of the body and 12 bone marrow sites. Estimates of the mean and median organ doses, standard deviations and ranges have been tabulated. Detailed distributions are presented for six organs (lung, bronchi, stomach, oesophagus, active bone marrow and total body). Comparison with the earlier bone marrow estimates and more recent estimates shows good agreement.
212-220
Lewis, C. A.
868ee1bb-aa8d-4113-9340-dd2a6f607712
Smith, P. G.
8979668a-8b7a-4838-9a74-1a7cfc6665f6
Stratton, I. M.
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Darby, S. C.
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Doll, R.
d5893e51-3c02-46e3-90c1-0f7305246f5c
1988
Lewis, C. A.
868ee1bb-aa8d-4113-9340-dd2a6f607712
Smith, P. G.
8979668a-8b7a-4838-9a74-1a7cfc6665f6
Stratton, I. M.
772f25b9-23c0-4240-a3f6-1e76b03b172f
Darby, S. C.
4c3e1c76-d404-4ff3-86f8-84e42fbb7970
Doll, R.
d5893e51-3c02-46e3-90c1-0f7305246f5c
Lewis, C. A., Smith, P. G., Stratton, I. M., Darby, S. C. and Doll, R.
(1988)
Estimated radiation doses to different organs among patients treated for ankylosing spondylitis with a single course of X rays.
British Journal of Radiology, 61 (723), .
(doi:10.1259/0007-1285-61-723-212).
Abstract
A follow-up study of over 14000 patients treated with a single course of X rays for ankylosing spondylitis demonstrated a substantial excess risk of developing cancer. Previously the excess risk of leukaemia has been related to the estimated mean radiation dose to the active bone marrow but detailed estimates were not made of the radiation doses to other organs. In the present work, data extracted from the original treatment records of a random sample of one in 15 patients have been used to make dose estimates, using Monte Carlo methods, for 30 specific organs or regions of the body and 12 bone marrow sites. Estimates of the mean and median organ doses, standard deviations and ranges have been tabulated. Detailed distributions are presented for six organs (lung, bronchi, stomach, oesophagus, active bone marrow and total body). Comparison with the earlier bone marrow estimates and more recent estimates shows good agreement.
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Published date: 1988
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Local EPrints ID: 486936
URI: http://eprints.soton.ac.uk/id/eprint/486936
ISSN: 0007-1285
PURE UUID: 4fa835e7-cfa3-4f85-94f8-035d79a7e540
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Date deposited: 08 Feb 2024 17:45
Last modified: 18 Mar 2024 04:01
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Author:
C. A. Lewis
Author:
I. M. Stratton
Author:
R. Doll
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