Diagnosis of diabetes: HbA1c versus WHO criteria
Diagnosis of diabetes: HbA1c versus WHO criteria
The authors compared the diagnosis of type 2 diabetes using an HbA 1c cut-off point of ≥6.5% (≥48 mmol/mol) with current World Health Organization (WHO) criteria involving fasting plasma glucose and an oral glucose tolerance test. Diabetes was confirmed in 35% of Australian and 49% of UK participants using WHO criteria and a similar prevalence was obtained using HbA1c - 31% and 46%, respectively. Using HbA1c levels alone for diagnosis does not define the same people with diabetes as the WHO criteria. A considerable number of participants (38% of Australian and 49% of British) diagnosed with diabetes by WHO criteria would not have been diagnosed using a single HbA1c test. More consideration of the use of HbA 1c as a screening test for diabetes is required.
Diagnosis, HbA, Sensitivity, Specificity
87-96
Stratton, Irene
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Gough, Stephen
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Cramb, Robert
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Smith, Janet
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Sikaris, Kenneth
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Nightingale, Peter
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Manley, Susan
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16 April 2010
Stratton, Irene
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Gough, Stephen
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Cramb, Robert
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Smith, Janet
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Sikaris, Kenneth
34f93551-c48a-4cb1-b4b3-2af1d6e1247c
Nightingale, Peter
643f789b-872d-4d35-8b85-89cf26ac3020
Manley, Susan
46bacfff-cf40-4894-86d8-4aa07e302e70
Stratton, Irene, Gough, Stephen, Cramb, Robert, Smith, Janet, Sikaris, Kenneth, Nightingale, Peter and Manley, Susan
(2010)
Diagnosis of diabetes: HbA1c versus WHO criteria.
Diabetes and Primary Care, 12 (2), .
Abstract
The authors compared the diagnosis of type 2 diabetes using an HbA 1c cut-off point of ≥6.5% (≥48 mmol/mol) with current World Health Organization (WHO) criteria involving fasting plasma glucose and an oral glucose tolerance test. Diabetes was confirmed in 35% of Australian and 49% of UK participants using WHO criteria and a similar prevalence was obtained using HbA1c - 31% and 46%, respectively. Using HbA1c levels alone for diagnosis does not define the same people with diabetes as the WHO criteria. A considerable number of participants (38% of Australian and 49% of British) diagnosed with diabetes by WHO criteria would not have been diagnosed using a single HbA1c test. More consideration of the use of HbA 1c as a screening test for diabetes is required.
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dpc12-2-87-96-1
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Published date: 16 April 2010
Keywords:
Diagnosis, HbA, Sensitivity, Specificity
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Local EPrints ID: 487127
URI: http://eprints.soton.ac.uk/id/eprint/487127
ISSN: 1466-8955
PURE UUID: 6e4b2cd8-e15d-44cd-b526-11ea7e3b7e2c
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Date deposited: 14 Feb 2024 17:37
Last modified: 18 Mar 2024 04:01
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Contributors
Author:
Irene Stratton
Author:
Stephen Gough
Author:
Robert Cramb
Author:
Janet Smith
Author:
Kenneth Sikaris
Author:
Peter Nightingale
Author:
Susan Manley
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