The University of Southampton
University of Southampton Institutional Repository

Asthma and rhinitis control in adolescents and young adults: a real-world MASK-air study

Asthma and rhinitis control in adolescents and young adults: a real-world MASK-air study
Asthma and rhinitis control in adolescents and young adults: a real-world MASK-air study

Background: in allergic rhinitis and asthma, adolescents and young adult patients are likely to differ from older patients. We compared adolescents, young adults and adults on symptoms, control levels, and medication adherence.

Methods: in a cross-sectional study (2015-2022), we assessed European users of the MASK-air mHealth app of three age groups: adolescents (13-18 years), young adults (18-26 years), and adults (>26 years). We compared them on their reported rhinitis and asthma symptoms, use and adherence to rhinitis and asthma treatment and app adherence. Allergy symptoms and control were assessed by means of visual analogue scales (VASs) on rhinitis or asthma, the combined symptom-medication score (CSMS), and the electronic daily control score for asthma (e-DASTHMA). We built multivariable regression models to compare symptoms or medication accounting for potential differences in demographic characteristics and baseline severity.

Results: we assessed 965 adolescent users (15,252 days), 4595 young adults (58,161 days), and 15,154 adult users (258,796 days). Users of all three age groups displayed similar app adherence. In multivariable models, age groups were not found to significantly differ in their adherence to rhinitis or asthma medication. These models also found that adolescents reported lower VAS on global allergy, ocular, and asthma symptoms (as well as lower CSMS) than young adults and adults.

Conclusions: adolescents reported a better rhinitis and asthma control than young adults and adults, even though similar medication adherence levels were observed across age groups. These results pave the way for future studies on understanding how adolescents control their allergic diseases.

adherence, adolescents, allergic rhinitis, asthma, digital health, mHealth, real-world data
0905-6157
Sousa-Pinto, Bernardo
6f16e57f-0979-47af-83de-fbe725438293
Valiulis, Arunas
f514a422-b1e4-4c2b-a14b-bf1fbe0b7552
Melén, Erik
2251f526-b320-4636-ab44-6c5fb5bce777
Koppelman, Gerard H.
db8a0204-1f42-4273-a8a7-8575a43cd21f
Papadopoulos, Nikolaos G
9223b719-0eb4-444c-a3b8-3875c5f003d1
Makela, Mika
fa4b4af0-704c-43b0-b653-5661cfabc42a
Haahtela, Tari
d83edd3e-f55d-41c2-93af-4d410ab935f7
Bonini, Matteo
9d1c57e7-dc83-4eb2-9e1c-5cadd0c7fbf5
Braido, Fulvio
9253a9a2-55aa-41b1-8670-63a2ff46d5e8
Brussino, Luisa
f8321cad-612d-43f8-b9f4-165cd8bca2fc
Cruz, Alvaro A.
35c073a4-664c-42b0-9705-f3416d5f8ade
Fiocchi, Alessandro
84f49387-5e31-4760-93d2-65b552d43c57
Giovannini, Mattia
7fc36c50-742a-4a60-b45c-c41aec454707
Gemicioglu, Bilun
00b888d7-3c4a-4317-976f-5f67986aa072
Kulus, Marek
ecf230c2-0084-41d0-b2f5-f514e5fa9011
Kuna, Piotr
0982046a-9893-4920-842d-49f032302edc
Kupczyk, Maciej
ed0ca49c-5b08-4427-8c4b-a34a0d495c60
Kvedariene, Violeta
2c5f61e9-9859-4236-af66-e5a9a538d6d9
Larenas-Linnemann, Désirée E.
132d3c9d-018f-4999-a944-a1d856b5bc17
Louis, Renaud
9d9c7917-f095-4647-abdb-a9725f586170
Morais-Almeida, Mario
2825635a-ce1e-4b6e-8f71-3fcb3130064c
Niedoszytko, Marek
f63fbb76-ae4a-4842-861a-ba096872506f
Ollert, Markus
404c1f0b-0b00-485d-96e1-4d95f8244820
Pfaar, Oliver
4f28a125-c84f-4a5f-9112-1e8b62e4365e
Regateiro, Frederico S.
9808c397-a4c2-4250-83ed-1ea37be357d5
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Samolinski, Boleslaw
cd16d06b-feaf-4f5f-8bcc-26d9e21ec663
Savouré, Marine
1fc91d1b-e262-4460-a420-5b158e3d4bbf
Taborda-Barata, Luis
22795257-c58f-4136-8cb5-9391991d5437
Toppila-Salmi, Sanna
618a3bcf-b952-46cb-b710-86dfd8e7a88d
Ventura, Maria Teresa
5dd2a7cb-7eb9-4212-931c-8ca80285acc7
Vazquez-Ortiz, Marta
890eb8f6-2903-44dd-b494-36af021f7708
Vieira, Rafael José
66a4766b-336a-4abd-99d2-f0289a0192e5
Fonseca, Joao A.
ca00cfaf-1b9f-4177-a1f3-17a26b75bcdc
Yorgancioglu, Arzu
6c76d942-8521-4196-a5e8-3657c28da079
Zuberbier, Torsten
0c26e302-c8de-4e14-a699-a9746692e1ff
Anto, Josep M.
10b41b86-8bf2-4b5e-933e-408899989175
Bousquet, Jean
8065d130-faa7-4c8e-bf40-8d2899980c21
Pham-Thi, Nhân
c27abb54-8160-48ad-a27e-b8a402647fbb
MASK-air think tank
Sousa-Pinto, Bernardo
6f16e57f-0979-47af-83de-fbe725438293
Valiulis, Arunas
f514a422-b1e4-4c2b-a14b-bf1fbe0b7552
Melén, Erik
2251f526-b320-4636-ab44-6c5fb5bce777
Koppelman, Gerard H.
db8a0204-1f42-4273-a8a7-8575a43cd21f
Papadopoulos, Nikolaos G
9223b719-0eb4-444c-a3b8-3875c5f003d1
Makela, Mika
fa4b4af0-704c-43b0-b653-5661cfabc42a
Haahtela, Tari
d83edd3e-f55d-41c2-93af-4d410ab935f7
Bonini, Matteo
9d1c57e7-dc83-4eb2-9e1c-5cadd0c7fbf5
Braido, Fulvio
9253a9a2-55aa-41b1-8670-63a2ff46d5e8
Brussino, Luisa
f8321cad-612d-43f8-b9f4-165cd8bca2fc
Cruz, Alvaro A.
35c073a4-664c-42b0-9705-f3416d5f8ade
Fiocchi, Alessandro
84f49387-5e31-4760-93d2-65b552d43c57
Giovannini, Mattia
7fc36c50-742a-4a60-b45c-c41aec454707
Gemicioglu, Bilun
00b888d7-3c4a-4317-976f-5f67986aa072
Kulus, Marek
ecf230c2-0084-41d0-b2f5-f514e5fa9011
Kuna, Piotr
0982046a-9893-4920-842d-49f032302edc
Kupczyk, Maciej
ed0ca49c-5b08-4427-8c4b-a34a0d495c60
Kvedariene, Violeta
2c5f61e9-9859-4236-af66-e5a9a538d6d9
Larenas-Linnemann, Désirée E.
132d3c9d-018f-4999-a944-a1d856b5bc17
Louis, Renaud
9d9c7917-f095-4647-abdb-a9725f586170
Morais-Almeida, Mario
2825635a-ce1e-4b6e-8f71-3fcb3130064c
Niedoszytko, Marek
f63fbb76-ae4a-4842-861a-ba096872506f
Ollert, Markus
404c1f0b-0b00-485d-96e1-4d95f8244820
Pfaar, Oliver
4f28a125-c84f-4a5f-9112-1e8b62e4365e
Regateiro, Frederico S.
9808c397-a4c2-4250-83ed-1ea37be357d5
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Samolinski, Boleslaw
cd16d06b-feaf-4f5f-8bcc-26d9e21ec663
Savouré, Marine
1fc91d1b-e262-4460-a420-5b158e3d4bbf
Taborda-Barata, Luis
22795257-c58f-4136-8cb5-9391991d5437
Toppila-Salmi, Sanna
618a3bcf-b952-46cb-b710-86dfd8e7a88d
Ventura, Maria Teresa
5dd2a7cb-7eb9-4212-931c-8ca80285acc7
Vazquez-Ortiz, Marta
890eb8f6-2903-44dd-b494-36af021f7708
Vieira, Rafael José
66a4766b-336a-4abd-99d2-f0289a0192e5
Fonseca, Joao A.
ca00cfaf-1b9f-4177-a1f3-17a26b75bcdc
Yorgancioglu, Arzu
6c76d942-8521-4196-a5e8-3657c28da079
Zuberbier, Torsten
0c26e302-c8de-4e14-a699-a9746692e1ff
Anto, Josep M.
10b41b86-8bf2-4b5e-933e-408899989175
Bousquet, Jean
8065d130-faa7-4c8e-bf40-8d2899980c21
Pham-Thi, Nhân
c27abb54-8160-48ad-a27e-b8a402647fbb

Sousa-Pinto, Bernardo, Valiulis, Arunas and Melén, Erik , MASK-air think tank (2024) Asthma and rhinitis control in adolescents and young adults: a real-world MASK-air study. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 35 (2), [e14080]. (doi:10.1111/pai.14080).

Record type: Article

Abstract

Background: in allergic rhinitis and asthma, adolescents and young adult patients are likely to differ from older patients. We compared adolescents, young adults and adults on symptoms, control levels, and medication adherence.

Methods: in a cross-sectional study (2015-2022), we assessed European users of the MASK-air mHealth app of three age groups: adolescents (13-18 years), young adults (18-26 years), and adults (>26 years). We compared them on their reported rhinitis and asthma symptoms, use and adherence to rhinitis and asthma treatment and app adherence. Allergy symptoms and control were assessed by means of visual analogue scales (VASs) on rhinitis or asthma, the combined symptom-medication score (CSMS), and the electronic daily control score for asthma (e-DASTHMA). We built multivariable regression models to compare symptoms or medication accounting for potential differences in demographic characteristics and baseline severity.

Results: we assessed 965 adolescent users (15,252 days), 4595 young adults (58,161 days), and 15,154 adult users (258,796 days). Users of all three age groups displayed similar app adherence. In multivariable models, age groups were not found to significantly differ in their adherence to rhinitis or asthma medication. These models also found that adolescents reported lower VAS on global allergy, ocular, and asthma symptoms (as well as lower CSMS) than young adults and adults.

Conclusions: adolescents reported a better rhinitis and asthma control than young adults and adults, even though similar medication adherence levels were observed across age groups. These results pave the way for future studies on understanding how adolescents control their allergic diseases.

Text
Pediatric Allergy Immunology - 2024 - Sousa‐Pinto - Asthma and rhinitis control in adolescents and young adults A - Version of Record
Download (501kB)

More information

Accepted/In Press date: 15 January 2024
e-pub ahead of print date: 2 February 2024
Published date: 2 February 2024
Additional Information: Publisher Copyright: © 2024 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
Keywords: adherence, adolescents, allergic rhinitis, asthma, digital health, mHealth, real-world data

Identifiers

Local EPrints ID: 487220
URI: http://eprints.soton.ac.uk/id/eprint/487220
ISSN: 0905-6157
PURE UUID: 8a60c818-f3bd-4da0-bce9-b409183f5575
ORCID for Graham Roberts: ORCID iD orcid.org/0000-0003-2252-1248

Catalogue record

Date deposited: 16 Feb 2024 11:24
Last modified: 27 Apr 2024 01:42

Export record

Altmetrics

Contributors

Author: Bernardo Sousa-Pinto
Author: Arunas Valiulis
Author: Erik Melén
Author: Gerard H. Koppelman
Author: Nikolaos G Papadopoulos
Author: Mika Makela
Author: Tari Haahtela
Author: Matteo Bonini
Author: Fulvio Braido
Author: Luisa Brussino
Author: Alvaro A. Cruz
Author: Alessandro Fiocchi
Author: Mattia Giovannini
Author: Bilun Gemicioglu
Author: Marek Kulus
Author: Piotr Kuna
Author: Maciej Kupczyk
Author: Violeta Kvedariene
Author: Désirée E. Larenas-Linnemann
Author: Renaud Louis
Author: Mario Morais-Almeida
Author: Marek Niedoszytko
Author: Markus Ollert
Author: Oliver Pfaar
Author: Frederico S. Regateiro
Author: Graham Roberts ORCID iD
Author: Boleslaw Samolinski
Author: Marine Savouré
Author: Luis Taborda-Barata
Author: Sanna Toppila-Salmi
Author: Maria Teresa Ventura
Author: Marta Vazquez-Ortiz
Author: Rafael José Vieira
Author: Joao A. Fonseca
Author: Arzu Yorgancioglu
Author: Torsten Zuberbier
Author: Josep M. Anto
Author: Jean Bousquet
Author: Nhân Pham-Thi
Corporate Author: MASK-air think tank

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×