READ ME File For 'Dataset supporting the University of Southampton Doctoral Thesis "Characterisation of the human microglial Profile identified with translocator protein (TSPO) and its role in the pathophysiology and progression of Alzheimer’s disease"' Dataset DOI: 10.5258/SOTON/D2962 ReadMe Author: Emma F. Garland, University of Southampton ORCID ID: 0000-0002-8501-4326 This dataset supports the thesis entitled: Characterisation of the human microglial Profile identified with translocator protein (TSPO) and its role in the pathophysiology and progression of Alzheimer’s disease AWARDED BY: Univeristy of Southampton DATE OF AWARD: 2024 DESCRIPTION OF THE DATA Pathology data - collected via ImageJ macro for pixel intensity and collated in an Excel spreadsheet. Cell count data - collected via positive cell detection tool in QuPath software, collated in an Excel Spreadsheet. Genptyping data - collected via qPCR using TaqMan genotyping kit, collated in an Excel spreadsheet. MSD data - collected via MSD assay, collated in an Excel spreadsheet. Date of data collection: 2020-2023 Licence: ERGO 62445 Related projects/Funders: PhD Studentship from Alzheimer's Research UK (ARUK-PhD2019-016) Related publication: https://doi.org/10.1186/s12974-023-02869-9 https://doi.org/10.3389/fnins.2022.824888 Date that the file was created: February, 2024