Additive manufacturing of sustainable biomaterials for biomedical applications
Additive manufacturing of sustainable biomaterials for biomedical applications
Biopolymers are promising environmentally benign materials applicable in multifarious applications. They are especially favorable in implantable biomedical devices thanks to their excellent unique properties, including bioactivity, renewability, bioresorbability, biocompatibility, biodegradability and hydrophilicity. Additive manufacturing (AM) is a flexible and intricate manufacturing technology, which is widely used to fabricate biopolymer-based customized products and structures for advanced healthcare systems. Three-dimensional (3D) printing of these sustainable materials is applied in functional clinical settings including wound dressing, drug delivery systems, medical implants and tissue engineering. The present review highlights recent advancements in different types of biopolymers, such as proteins and polysaccharides, which are employed to develop different biomedical products by using extrusion, vat polymerization, laser and inkjet 3D printing techniques in addition to normal bioprinting and four-dimensional (4D) bioprinting techniques. This review also incorporates the influence of nanoparticles on the biological and mechanical performances of 3D-printed tissue scaffolds. This work also addresses current challenges as well as future developments of environmentally friendly polymeric materials manufactured through the AM techniques. Ideally, there is a need for more focused research on the adequate blending of these biodegradable biopolymers for achieving useful results in targeted biomedical areas. We envision that biopolymer-based 3D-printed composites have the potential to revolutionize the biomedical sector in the near future.
3D printing, Additive manufacturing, Biomedical, Biopolymers, Sustainable biomaterials, Tissue engineering
Arif, Zia Ullah
49914102-f4f6-417f-9881-22a80015dedf
Khalid, Muhammad Yasir
156549c9-dd36-42d8-a9d1-8118a3286d3f
Noroozi, Reza
73bcdd80-ae09-4acd-b461-97cc4a528727
Hossain, Mokarram
67bb0446-f78a-4021-b2b9-3d95fce006f9
Shi, Hao Tian Harvey
b8378899-df96-4878-aecf-67ca120b6cd0
Tariq, Ali
63a1b532-cf64-4608-a450-b011a32fae9b
Ramakrishna, Seeram
81b48cac-c096-4e00-bae2-595e05eaba99
Umer, Rehan
cdf372ed-5abe-46be-a34a-9107d8813ac3
26 May 2023
Arif, Zia Ullah
49914102-f4f6-417f-9881-22a80015dedf
Khalid, Muhammad Yasir
156549c9-dd36-42d8-a9d1-8118a3286d3f
Noroozi, Reza
73bcdd80-ae09-4acd-b461-97cc4a528727
Hossain, Mokarram
67bb0446-f78a-4021-b2b9-3d95fce006f9
Shi, Hao Tian Harvey
b8378899-df96-4878-aecf-67ca120b6cd0
Tariq, Ali
63a1b532-cf64-4608-a450-b011a32fae9b
Ramakrishna, Seeram
81b48cac-c096-4e00-bae2-595e05eaba99
Umer, Rehan
cdf372ed-5abe-46be-a34a-9107d8813ac3
Arif, Zia Ullah, Khalid, Muhammad Yasir, Noroozi, Reza, Hossain, Mokarram, Shi, Hao Tian Harvey, Tariq, Ali, Ramakrishna, Seeram and Umer, Rehan
(2023)
Additive manufacturing of sustainable biomaterials for biomedical applications.
Asian Journal of Pharmaceutical Sciences, 18 (3), [100812].
(doi:10.1016/j.ajps.2023.100812).
Abstract
Biopolymers are promising environmentally benign materials applicable in multifarious applications. They are especially favorable in implantable biomedical devices thanks to their excellent unique properties, including bioactivity, renewability, bioresorbability, biocompatibility, biodegradability and hydrophilicity. Additive manufacturing (AM) is a flexible and intricate manufacturing technology, which is widely used to fabricate biopolymer-based customized products and structures for advanced healthcare systems. Three-dimensional (3D) printing of these sustainable materials is applied in functional clinical settings including wound dressing, drug delivery systems, medical implants and tissue engineering. The present review highlights recent advancements in different types of biopolymers, such as proteins and polysaccharides, which are employed to develop different biomedical products by using extrusion, vat polymerization, laser and inkjet 3D printing techniques in addition to normal bioprinting and four-dimensional (4D) bioprinting techniques. This review also incorporates the influence of nanoparticles on the biological and mechanical performances of 3D-printed tissue scaffolds. This work also addresses current challenges as well as future developments of environmentally friendly polymeric materials manufactured through the AM techniques. Ideally, there is a need for more focused research on the adequate blending of these biodegradable biopolymers for achieving useful results in targeted biomedical areas. We envision that biopolymer-based 3D-printed composites have the potential to revolutionize the biomedical sector in the near future.
Text
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Accepted/In Press date: 30 March 2023
e-pub ahead of print date: 27 April 2023
Published date: 26 May 2023
Keywords:
3D printing, Additive manufacturing, Biomedical, Biopolymers, Sustainable biomaterials, Tissue engineering
Identifiers
Local EPrints ID: 488083
URI: http://eprints.soton.ac.uk/id/eprint/488083
ISSN: 1818-0876
PURE UUID: 116ce149-6dd1-4321-9d64-4d10b4142b21
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Date deposited: 15 Mar 2024 17:31
Last modified: 18 Mar 2024 04:14
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Contributors
Author:
Zia Ullah Arif
Author:
Muhammad Yasir Khalid
Author:
Reza Noroozi
Author:
Mokarram Hossain
Author:
Hao Tian Harvey Shi
Author:
Ali Tariq
Author:
Seeram Ramakrishna
Author:
Rehan Umer
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