A quantitative and qualitative evaluation of LISA, a decision support system for chemotherapy dosing in childhood acute lymphoblastic leukaemia

Bury, Jonathan, Hurt, Chris, Roy, Anindita, Bradburn, Mike, Cross, Simon, Fox, John and Saha, Vaskar (2004) A quantitative and qualitative evaluation of LISA, a decision support system for chemotherapy dosing in childhood acute lymphoblastic leukaemia. Studies in Health Technology and Informatics, 107, 197-201.

Abstract

Objectives: to assess the acceptability to clinicians of a web-based decision support system designed to assist with dosage adjustments during maintenance therapy for childhood Acute Lymphoblastic Leukaemia (ALL), and to evaluate the potential impact of the system on decision-making and dosage calculations.

Design: balanced-block crossover experiment with simulated cases; questionnaire study and semi-structured interviews.

Participants: 36 clinicians with differing experience in the management of ALL.

Interventions: subjects were asked to decide on appropriate levels of chemotherapy dosing for 8 simulated cases, 4 using the LISA decision support system, 4 using conventional paper-based records and guidance.

Main outcome measures: number of protocol-consistent dosage decisions made; time taken to manage each case; accuracy of dosage calculations; subjects' opinions as to whether or not they would use the system in practice. ADDITIONAL OUTCOME MEASURES: Functions subjects would like to see in an idealised system; subjects' satisfaction with the implementation of the functions provided by LISA; qualitative data on issues subjects felt would impact upon the successful deployment of the system.

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Contributors

Author: Chris Hurt

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