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The role and uses of antibodies in COVID-19 infections: a living review

The role and uses of antibodies in COVID-19 infections: a living review
The role and uses of antibodies in COVID-19 infections: a living review
Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.
Scourfield, D. Oliver
55d54bf5-818b-4cce-adf9-d43e0829602e
Reed, Sophie G.
1ff2b2c8-d9e0-4423-9bd4-5df2bb7374b0
Quastel, Max
0ad52505-deac-4154-a512-d9caab10b50d
Wann, Angus
f1b0ea2f-dc8a-4588-a9d8-ae462ed0a993
et al.
The Oxford-Cardiff COVID-19 Literature Consortium
Scourfield, D. Oliver
55d54bf5-818b-4cce-adf9-d43e0829602e
Reed, Sophie G.
1ff2b2c8-d9e0-4423-9bd4-5df2bb7374b0
Quastel, Max
0ad52505-deac-4154-a512-d9caab10b50d
Wann, Angus
f1b0ea2f-dc8a-4588-a9d8-ae462ed0a993

Scourfield, D. Oliver, Reed, Sophie G. and Quastel, Max , et al. and The Oxford-Cardiff COVID-19 Literature Consortium (2021) The role and uses of antibodies in COVID-19 infections: a living review. Oxford Open Immunology, 2 (1), [iqab003]. (doi:10.1093/oxfimm/iqab003).

Record type: Article

Abstract

Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.

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Accepted/In Press date: 7 January 2021
Published date: 28 January 2021

Identifiers

Local EPrints ID: 488389
URI: http://eprints.soton.ac.uk/id/eprint/488389
PURE UUID: 6df5e2f9-d22b-4159-9980-0e7d30b58bfd
ORCID for Angus Wann: ORCID iD orcid.org/0000-0002-8224-8661

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Date deposited: 21 Mar 2024 17:37
Last modified: 23 Mar 2024 03:11

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Contributors

Author: D. Oliver Scourfield
Author: Sophie G. Reed
Author: Max Quastel
Author: Angus Wann ORCID iD
Corporate Author: et al.
Corporate Author: The Oxford-Cardiff COVID-19 Literature Consortium

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