A country-specific FRAX model for Botswana
A country-specific FRAX model for Botswana
Introduction: hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment.
Objective: this paper describes the development and characteristics of a country-specific FRAX model for Botswana.
Methods: age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA.
Results: the probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia.
Conclusion: the creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.
Botswana, Female, Hip Fractures, Humans, Male, Osteoporotic Fractures, Risk Assessment, Risk Factors, South Africa
Kebaetse, M.
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Nkhwa, S.
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Mogodi, M.
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Masunge, J.
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Gureja, Y.P.
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Ramabu, M.
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Mmopelwa, T.
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Sharif, I.
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Orford, A.
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Harvey, N.C.
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McCloskey, E.V.
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Cauley, J.A.
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Kanis, J.A.
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Johansson, H.
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7 June 2021
Kebaetse, M.
e689e3c9-004d-45da-8670-1aa33a8f1fbd
Nkhwa, S.
1cc6e490-5120-439e-8501-74f870e49ad2
Mogodi, M.
9289969a-e6e9-4415-b91f-772c18aaab05
Masunge, J.
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Gureja, Y.P.
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Ramabu, M.
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Mmopelwa, T.
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Sharif, I.
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Orford, A.
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Harvey, N.C.
ce487fb4-d360-4aac-9d17-9466d6cba145
McCloskey, E.V.
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Cauley, J.A.
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Kanis, J.A.
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Johansson, H.
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Kebaetse, M., Nkhwa, S., Mogodi, M., Masunge, J., Gureja, Y.P., Ramabu, M., Mmopelwa, T., Sharif, I., Orford, A., Harvey, N.C., McCloskey, E.V., Cauley, J.A., Kanis, J.A. and Johansson, H.
(2021)
A country-specific FRAX model for Botswana.
Archives of Osteoporosis, 16 (1).
(doi:10.1007/s11657-021-00965-y).
Abstract
Introduction: hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment.
Objective: this paper describes the development and characteristics of a country-specific FRAX model for Botswana.
Methods: age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA.
Results: the probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia.
Conclusion: the creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.
Text
s11657-021-00965-y
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Accepted/In Press date: 12 April 2021
Published date: 7 June 2021
Keywords:
Botswana, Female, Hip Fractures, Humans, Male, Osteoporotic Fractures, Risk Assessment, Risk Factors, South Africa
Identifiers
Local EPrints ID: 488506
URI: http://eprints.soton.ac.uk/id/eprint/488506
ISSN: 1862-3522
PURE UUID: 424e7f03-c459-42ac-94bf-ee587d7c0b95
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Date deposited: 25 Mar 2024 17:39
Last modified: 26 Mar 2024 02:38
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Contributors
Author:
M. Kebaetse
Author:
S. Nkhwa
Author:
M. Mogodi
Author:
J. Masunge
Author:
Y.P. Gureja
Author:
M. Ramabu
Author:
T. Mmopelwa
Author:
I. Sharif
Author:
A. Orford
Author:
E.V. McCloskey
Author:
J.A. Cauley
Author:
J.A. Kanis
Author:
H. Johansson
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