READ ME File For 'Datasets in support of  Southampton Doctoral Thesis 'Investigating the regulation, function, and clinical significance of PDCD4 in B-cell neoplasms''

Dataset DOI: 10.5258/SOTON/D2293

ReadMe Author: Joseph William Taylor, University of Southampton

This dataset supports the thesis entitled 'Investigating the regulation, function, and clinical significance of PDCD4 in B-cell neoplasms'
AWARDED BY: Univeristy of Southampton
DATE OF AWARD: [June 2022]


DESCRIPTION OF THE DATA

This dataset series contains:
Figures: emf files showing individual figures for thesis results chapters
Blots: Individual western blot images for immunoblotting experiments
LogFC: RNAseq log fold change values from experiments


the files are embargoed to 1 July 2025:
Figures.7z
LogFC_datasets.zip
blots.7z

Date of data collection: [25/9/2017 - 1/1/2022]

Information about geographic location of data collection: Somers Cancer Research Building, General Hospital,, Southampton SO16 6YD

Licence:
[CC BY]

Related projects/Funders:
[MRC (PhD sponsor), CRUK (lab funder)]


Related publication:
Joe Taylor et al (2022) B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells,
Cellular Signalling, Vol 94, 2022, 110311,
ISSN 0898-6568,
https://doi.org/10.1016/j.cellsig.2022.110311.



Date that the file was created: March, 2024