Variant Creutzfeldt-Jakob disease: neuropsychological profile in an extended series of cases.
Variant Creutzfeldt-Jakob disease: neuropsychological profile in an extended series of cases.
Neuropsychological data on an extended series of cases of variant Creutzfeldt-Jakob Disease (vCJD) are presented, complementing earlier findings from smaller sample studies of this condition. Distinct neuropsychological features in this extended series included relatively preserved verbal knowledge, immediate verbal memory span, and elementary visual processing. This sparing contrasted with ubiquitous impairment in every vCJD patient on timed tests of verbal fluency and digit-symbol substitution. There were also high rates of impairment on tests of memory, and of visuoperceptual and visuospatial reasoning. Our findings lend support to the view that distinctive neuropsychological features may be one of the diagnostic markers of the condition. (JINS, 2009, 15, 807–810.)
807-809
Hawkins, Kari
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Chohan, Gurjit
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Kipps, Christopher
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Will, Robert
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Kapur, Narinder
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1 September 2009
Hawkins, Kari
f2f9d9ee-9e96-4485-9f29-619c11485c38
Chohan, Gurjit
da110818-5f4b-4c31-ad73-9d395b3a229d
Kipps, Christopher
e43be016-2dc2-45e6-9a02-ab2a0e0208d5
Will, Robert
16903a2f-f665-4b2e-8622-29834a8ce2e1
Kapur, Narinder
f713a6d9-5625-4492-81fb-75801b6cb12a
Hawkins, Kari, Chohan, Gurjit, Kipps, Christopher, Will, Robert and Kapur, Narinder
(2009)
Variant Creutzfeldt-Jakob disease: neuropsychological profile in an extended series of cases.
Journal of the International Neuropsychological Society, 15 (5), .
(doi:10.1017/s1355617709990397).
Abstract
Neuropsychological data on an extended series of cases of variant Creutzfeldt-Jakob Disease (vCJD) are presented, complementing earlier findings from smaller sample studies of this condition. Distinct neuropsychological features in this extended series included relatively preserved verbal knowledge, immediate verbal memory span, and elementary visual processing. This sparing contrasted with ubiquitous impairment in every vCJD patient on timed tests of verbal fluency and digit-symbol substitution. There were also high rates of impairment on tests of memory, and of visuoperceptual and visuospatial reasoning. Our findings lend support to the view that distinctive neuropsychological features may be one of the diagnostic markers of the condition. (JINS, 2009, 15, 807–810.)
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Accepted/In Press date: 15 June 2009
Published date: 1 September 2009
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Local EPrints ID: 489388
URI: http://eprints.soton.ac.uk/id/eprint/489388
PURE UUID: 5be6f9ac-adac-4e1c-aa50-6877c0f1090c
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Date deposited: 23 Apr 2024 16:34
Last modified: 24 Apr 2024 01:56
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Author:
Kari Hawkins
Author:
Gurjit Chohan
Author:
Christopher Kipps
Author:
Robert Will
Author:
Narinder Kapur
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