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Conditions for optic axon outgrowth

Conditions for optic axon outgrowth
Conditions for optic axon outgrowth

A series of studies is described which show that retinai axon outgrowth can be stimulated by the close proximity of an appropriate target region. The suggestion is offered that, in normal development, optic axons first follow cues available at the surface of the brainstem, but once they reach a target region, ramify there in response to the presence of a target-derived factor.

Axonal guidance, Neural transplants, Visual system
0006-8977
218-226
Lund, R. D.
8f391e75-95a0-4058-9b86-eb94b8f2fbe6
Hankin, M. H.
50814c49-bf96-4b02-b6dc-e3b287d7b23a
Seflon, A. J.
6f6cd0a0-63f1-4f70-86aa-4743a560bdd3
Perry, V. H.
8f29d36a-8e1f-4082-8700-09483bbaeae4
Lund, R. D.
8f391e75-95a0-4058-9b86-eb94b8f2fbe6
Hankin, M. H.
50814c49-bf96-4b02-b6dc-e3b287d7b23a
Seflon, A. J.
6f6cd0a0-63f1-4f70-86aa-4743a560bdd3
Perry, V. H.
8f29d36a-8e1f-4082-8700-09483bbaeae4

Lund, R. D., Hankin, M. H., Seflon, A. J. and Perry, V. H. (1988) Conditions for optic axon outgrowth. Brain, Behavior and Evolution, 31 (4), 218-226. (doi:10.1159/000116590).

Record type: Article

Abstract

A series of studies is described which show that retinai axon outgrowth can be stimulated by the close proximity of an appropriate target region. The suggestion is offered that, in normal development, optic axons first follow cues available at the surface of the brainstem, but once they reach a target region, ramify there in response to the presence of a target-derived factor.

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More information

Published date: 1988
Keywords: Axonal guidance, Neural transplants, Visual system
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Identifiers

Local EPrints ID: 489398
URI: http://eprints.soton.ac.uk/id/eprint/489398
DOI: doi:10.1159/000116590
ISSN: 0006-8977
PURE UUID: 9ce7a4ad-3bd8-4502-a522-ea36a6aaddcd

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Date deposited: 23 Apr 2024 16:43
Last modified: 23 Apr 2024 16:43

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Contributors

Author: R. D. Lund
Author: M. H. Hankin
Author: A. J. Seflon
Author: V. H. Perry

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