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Macrophages and microglia in the nervous system

Macrophages and microglia in the nervous system
Macrophages and microglia in the nervous system

Why might macrophages be of interest to neurobiologists? Recent evidence shows that macrophages play a role in tissue homeostasis as well as in defence and repair of tissues. We will review here the possible functions of resident and recruited macrophages in the developing and adult nervous system and examine what contribution these cells might make to repair mechanisms in the central and peripheral nervous systems. There is increasing evidence that macrophages form an important component of the non-neuronal cell population in the nervous system and the tools are becoming available that allow us to study these cells in situ.

0166-2236
273-277
Perry, V. Hugh
8f29d36a-8e1f-4082-8700-09483bbaeae4
Gordon, Siamon
df664ae8-6319-4b1a-8f16-49f4a5fe760f
Perry, V. Hugh
8f29d36a-8e1f-4082-8700-09483bbaeae4
Gordon, Siamon
df664ae8-6319-4b1a-8f16-49f4a5fe760f

Perry, V. Hugh and Gordon, Siamon (1988) Macrophages and microglia in the nervous system. Trends in Neurosciences, 11 (6), 273-277. (doi:10.1016/0166-2236(88)90110-5).

Record type: Review

Abstract

Why might macrophages be of interest to neurobiologists? Recent evidence shows that macrophages play a role in tissue homeostasis as well as in defence and repair of tissues. We will review here the possible functions of resident and recruited macrophages in the developing and adult nervous system and examine what contribution these cells might make to repair mechanisms in the central and peripheral nervous systems. There is increasing evidence that macrophages form an important component of the non-neuronal cell population in the nervous system and the tools are becoming available that allow us to study these cells in situ.

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Published date: 1988

Identifiers

Local EPrints ID: 489401
URI: http://eprints.soton.ac.uk/id/eprint/489401
ISSN: 0166-2236
PURE UUID: 1aa50901-efc7-469d-8037-76d9bd385ff0

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Date deposited: 23 Apr 2024 16:44
Last modified: 05 Jun 2024 17:36

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Contributors

Author: V. Hugh Perry
Author: Siamon Gordon

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