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Biology of the mononuclear phagocyte system of the central nervous system and HIV infection

Biology of the mononuclear phagocyte system of the central nervous system and HIV infection
Biology of the mononuclear phagocyte system of the central nervous system and HIV infection

Infection of the central nervous system by HIV-1 results in widespread neuropathology and neurological symptoms. The cells infected in the brain belong to the mononuclear phagocyte lineage. We review aspects of the biology of the macrophage populations associated with the central nervous system and consider their distribution, phenotype, and kinetics in relation to HIV pathology.

central nervous system, HIV, macrophage, microglia
0741-5400
399-406
Perry, V.H.
8f29d36a-8e1f-4082-8700-09483bbaeae4
Lawson, L.J.
f4776a41-ec67-451a-a3b6-bb6720195746
Reid, D.M
7da9b4a1-afb9-482e-a2e4-294337c64cf5
Perry, V.H.
8f29d36a-8e1f-4082-8700-09483bbaeae4
Lawson, L.J.
f4776a41-ec67-451a-a3b6-bb6720195746
Reid, D.M
7da9b4a1-afb9-482e-a2e4-294337c64cf5

Perry, V.H., Lawson, L.J. and Reid, D.M (1994) Biology of the mononuclear phagocyte system of the central nervous system and HIV infection. Journal of Leukocyte Biology, 56 (3), 399-406. (doi:10.1002/jlb.56.3.399).

Record type: Review

Abstract

Infection of the central nervous system by HIV-1 results in widespread neuropathology and neurological symptoms. The cells infected in the brain belong to the mononuclear phagocyte lineage. We review aspects of the biology of the macrophage populations associated with the central nervous system and consider their distribution, phenotype, and kinetics in relation to HIV pathology.

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More information

Accepted/In Press date: 29 March 1994
Published date: 1 September 1994
Keywords: central nervous system, HIV, macrophage, microglia
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Identifiers

Local EPrints ID: 489573
URI: http://eprints.soton.ac.uk/id/eprint/489573
DOI: doi:10.1002/jlb.56.3.399
ISSN: 0741-5400
PURE UUID: ee653359-b045-4d04-b6d5-60ed34089110

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Date deposited: 29 Apr 2024 16:31
Last modified: 29 Apr 2024 16:31

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Contributors

Author: V.H. Perry
Author: L.J. Lawson
Author: D.M Reid

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