Anthony, D.C. and Perry, V.H. (1998) Stroke: a double-edged sword for cleaving clots? Current Biology, 8 (8), R274-R277. (doi:10.1016/s0960-9822(98)70171-x).
Abstract
The discovery that tissue plasminogen activator can promote neuronal degeneration has uncovered a novel pathway leading to neuronal cell death and raises important issues concerning the use of tissue plasminogen activator as a thrombolytic therapy for stroke.
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