Does radiolabelled diphosphonate retention reflect bone metabolism in the elderly?
Does radiolabelled diphosphonate retention reflect bone metabolism in the elderly?
The 24-h whole-body retention of diphosphonates (WBR), a useful measure of bone metabolism in young subjects, was measured in 27 elderly subjects (19 from home and eight in-patients). WBR rose with increasing age (r=0.55, P<0.01) and was negatively correlated with renal function (r= -0.60, P<0.01). In five subjects given vitamin D, WBR did not fall. The measurement of WBR in the elderly has to be assessed in the light of an accurate assessment of renal function and so is rarely clinically useful.
164-168
Webb, A.J.
aa869431-806a-43ab-addf-83ef5096e8d9
Sinha, B.
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Briggs, R.S.J.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Ackery, D.
a78030f2-e20f-4e5c-b094-7599c01894cb
1 May 1986
Webb, A.J.
aa869431-806a-43ab-addf-83ef5096e8d9
Sinha, B.
544b5a07-3d74-464b-9470-a68c69bd722e
Briggs, R.S.J.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Ackery, D.
a78030f2-e20f-4e5c-b094-7599c01894cb
Webb, A.J., Sinha, B., Briggs, R.S.J. and Ackery, D.
(1986)
Does radiolabelled diphosphonate retention reflect bone metabolism in the elderly?
Age and Ageing, 15 (3), .
(doi:10.1093/ageing/15.3.164).
Abstract
The 24-h whole-body retention of diphosphonates (WBR), a useful measure of bone metabolism in young subjects, was measured in 27 elderly subjects (19 from home and eight in-patients). WBR rose with increasing age (r=0.55, P<0.01) and was negatively correlated with renal function (r= -0.60, P<0.01). In five subjects given vitamin D, WBR did not fall. The measurement of WBR in the elderly has to be assessed in the light of an accurate assessment of renal function and so is rarely clinically useful.
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Accepted/In Press date: 12 December 1985
Published date: 1 May 1986
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Local EPrints ID: 490664
URI: http://eprints.soton.ac.uk/id/eprint/490664
ISSN: 0002-0729
PURE UUID: 9850552e-2bf2-499e-838d-35e709d369bd
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Date deposited: 03 Jun 2024 16:31
Last modified: 03 Jun 2024 16:31
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Author:
A.J. Webb
Author:
B. Sinha
Author:
R.S.J. Briggs
Author:
D. Ackery
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