Continuous flow separation of particles within an asymmetric microfluidic device
Continuous flow separation of particles within an asymmetric microfluidic device
A microfluidic based device has been developed for the continuous separation of polymer microspheres, taking advantage of the flow characteristics of systems. The chip consists of an asymmetric cavity with variable channel width which enables continuous amplification of the particle separation for different size particles within the laminar flow profile. The process has been examined by varying the sample inlet position, the sample to media flow rate ratio, and the total flow rate. This technique can be applied for manipulating both microscale biological and colloidal particles within microfluidic systems.
561-566
Zhang, X.
d7cf1181-3276-4da1-9150-e212b333abb1
Cooper, J.M.
2989de71-0927-4b73-828c-a70929ff00c5
Monaghan, P.B.
8debb927-cde8-4ac4-adb1-d8c3570e1faf
Haswell, S.J.
7a1bc2cc-4cdf-4092-976c-5ebf65107eaa
13 March 2006
Zhang, X.
d7cf1181-3276-4da1-9150-e212b333abb1
Cooper, J.M.
2989de71-0927-4b73-828c-a70929ff00c5
Monaghan, P.B.
8debb927-cde8-4ac4-adb1-d8c3570e1faf
Haswell, S.J.
7a1bc2cc-4cdf-4092-976c-5ebf65107eaa
Zhang, X., Cooper, J.M., Monaghan, P.B. and Haswell, S.J.
(2006)
Continuous flow separation of particles within an asymmetric microfluidic device.
Lab on a Chip, 6 (4), .
(doi:10.1039/b515272k).
Abstract
A microfluidic based device has been developed for the continuous separation of polymer microspheres, taking advantage of the flow characteristics of systems. The chip consists of an asymmetric cavity with variable channel width which enables continuous amplification of the particle separation for different size particles within the laminar flow profile. The process has been examined by varying the sample inlet position, the sample to media flow rate ratio, and the total flow rate. This technique can be applied for manipulating both microscale biological and colloidal particles within microfluidic systems.
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Published date: 13 March 2006
Identifiers
Local EPrints ID: 49135
URI: http://eprints.soton.ac.uk/id/eprint/49135
ISSN: 1473-0197
PURE UUID: 2732b2d7-fa27-4a22-8546-f7ef6e4cf66f
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Date deposited: 24 Oct 2007
Last modified: 16 Mar 2024 03:55
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Contributors
Author:
J.M. Cooper
Author:
P.B. Monaghan
Author:
S.J. Haswell
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