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Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: a prospective cohort study in primary care

Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: a prospective cohort study in primary care
Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: a prospective cohort study in primary care
In older adults, reduced social participation increases the risk of poor health-related quality of life, increased levels of inflammatory markers and cardiovascular disease, and increased mortality. Older adults frequently present to primary care, which offers the potential to deliver interventions at the point of care to increase social participation. The aim of this prospective study was to identify the key modifiable exposures that were associated with reduced social participation in a primary care population of older adults.

The study was a population-based prospective cohort study. Participants (n = 1991) were those aged ≥65 years who had completed questionnaires at baseline, and 3 and 6-year follow-ups. Generalized linear mixed modeling framework was used to test for associations between exposures and decreasing social participation over 6 years.

At baseline, 44% of participants reported reduced social participation, increasing to 49% and 55% at 3 and 6-year follow-up. Widespread pain and depression had the strongest independent association with reduced social participation over the 6-year follow-up period. The prevalence of reduced social participation for those with widespread pain was 106% (adjusted incidence rate ratio 2.06, 95% confidence interval 1.72, 2.46), higher than for those with no pain. Those with depression had an increased prevalence of 82% (adjusted incidence rate ratio 1.82, 95% confidence interval 1.62, 2.06). These associations persisted in multivariate analysis.

Population ageing will be accompanied by increasing numbers of older adults with pain and depression. Future trials should assess whether screening for widespread pain and depression, and targeting appropriate treatment in primary care, increase social participation in older people.
1357-3039
Wilkie, Ross
873607f2-f09d-4dd4-8794-878b5491781a
Blagojevic-Bucknall, Milisa
b6ecad56-f51c-40cd-b06a-a3a8a8a1fd21
Belcher, John
1103137a-085e-4f85-9323-740ca462d6df
Chew-Graham, Carolyn
291893ce-f136-4dc3-8a63-3d2294446b3b
Lacey, Rosie J.
6a5ba7da-7730-4e36-9448-7291d24f9809
McBeth, John
98012716-66ba-480b-9e43-ac53b51dce61
Wilkie, Ross
873607f2-f09d-4dd4-8794-878b5491781a
Blagojevic-Bucknall, Milisa
b6ecad56-f51c-40cd-b06a-a3a8a8a1fd21
Belcher, John
1103137a-085e-4f85-9323-740ca462d6df
Chew-Graham, Carolyn
291893ce-f136-4dc3-8a63-3d2294446b3b
Lacey, Rosie J.
6a5ba7da-7730-4e36-9448-7291d24f9809
McBeth, John
98012716-66ba-480b-9e43-ac53b51dce61

Wilkie, Ross, Blagojevic-Bucknall, Milisa, Belcher, John, Chew-Graham, Carolyn, Lacey, Rosie J. and McBeth, John (2016) Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: a prospective cohort study in primary care. Medicine, 95 (31), [e4111]. (doi:10.1097/md.0000000000004111).

Record type: Article

Abstract

In older adults, reduced social participation increases the risk of poor health-related quality of life, increased levels of inflammatory markers and cardiovascular disease, and increased mortality. Older adults frequently present to primary care, which offers the potential to deliver interventions at the point of care to increase social participation. The aim of this prospective study was to identify the key modifiable exposures that were associated with reduced social participation in a primary care population of older adults.

The study was a population-based prospective cohort study. Participants (n = 1991) were those aged ≥65 years who had completed questionnaires at baseline, and 3 and 6-year follow-ups. Generalized linear mixed modeling framework was used to test for associations between exposures and decreasing social participation over 6 years.

At baseline, 44% of participants reported reduced social participation, increasing to 49% and 55% at 3 and 6-year follow-up. Widespread pain and depression had the strongest independent association with reduced social participation over the 6-year follow-up period. The prevalence of reduced social participation for those with widespread pain was 106% (adjusted incidence rate ratio 2.06, 95% confidence interval 1.72, 2.46), higher than for those with no pain. Those with depression had an increased prevalence of 82% (adjusted incidence rate ratio 1.82, 95% confidence interval 1.62, 2.06). These associations persisted in multivariate analysis.

Population ageing will be accompanied by increasing numbers of older adults with pain and depression. Future trials should assess whether screening for widespread pain and depression, and targeting appropriate treatment in primary care, increase social participation in older people.

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Accepted/In Press date: 9 June 2016
Published date: August 2016

Identifiers

Local EPrints ID: 491444
URI: http://eprints.soton.ac.uk/id/eprint/491444
ISSN: 1357-3039
PURE UUID: e2c601bd-e19e-4776-a099-4b281755343d
ORCID for John McBeth: ORCID iD orcid.org/0000-0001-7047-2183

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Date deposited: 24 Jun 2024 16:47
Last modified: 12 Jul 2024 02:17

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Contributors

Author: Ross Wilkie
Author: Milisa Blagojevic-Bucknall
Author: John Belcher
Author: Carolyn Chew-Graham
Author: Rosie J. Lacey
Author: John McBeth ORCID iD

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