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Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: Results from a population-based prospective study

Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: Results from a population-based prospective study
Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: Results from a population-based prospective study
Objective: to determine the relationship between physically traumatic events and the onset of chronic widespread pain (CWP).

Methods: this was a case–control study nested within a large prospective cohort. CWP was determined, by questionnaire, as per the American College of Rheumatology fibromyalgia classification criteria. Data were also collected on psychological health, health behavior, and sleep problems. Participants without CWP were then followed up at 4 years, and (new-onset) CWP was determined in the same manner. At followup, participants were also asked to report whether they had experienced any of a series of physically traumatic events between baseline and followup.

Results: a total of 2,069 individuals (46.6%) participated at followup, and 241 of these individuals (11.6%) reported CWP. More than one-third of the study population reported at least 1 physically traumatic event; although these individuals were more likely to develop CWP, this relationship was completely attenuated after adjustment for confounding (odds ratio 1.01, 95% confidence interval 0.73–1.40). However, there was some evidence to suggest that involvement in a road traffic accident, specifically, may confer an increase in the risk of CWP onset.

Conclusion: this study provides support for the “at risk” phenotype hypothesis, where individuals characterized by poorer health and psychological variables may be predisposed to develop CWP following a traumatic trigger. However, although this has been seen with road traffic accidents, it is not the case with other events. Future research should examine what is peculiar about an accident, or about one's reaction to it, that confers this increase in the risk of CWP onset.
0893-7524
696-701
Jones, Gareth T.
fdb7f584-21c5-4fe4-9e57-b58c78ebe3f5
Nicholl, Barbara I.
3922cf66-6e36-44d2-9d8b-1736123e0e53
McBeth, John
98012716-66ba-480b-9e43-ac53b51dce61
Davies, Kelly A.
064e8ade-de11-4e9b-9b9d-4bf9fe9a69e4
Morriss, Richard K.
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Dickens, Chris
a41afee4-9852-4e66-a96d-938151d8fd3a
MacFarlane, Gary J.
e17bbdb7-9d82-42ac-8a0a-09bf10885e3c
Jones, Gareth T.
fdb7f584-21c5-4fe4-9e57-b58c78ebe3f5
Nicholl, Barbara I.
3922cf66-6e36-44d2-9d8b-1736123e0e53
McBeth, John
98012716-66ba-480b-9e43-ac53b51dce61
Davies, Kelly A.
064e8ade-de11-4e9b-9b9d-4bf9fe9a69e4
Morriss, Richard K.
00605a7f-7555-48f9-81e1-9b0aed384722
Dickens, Chris
a41afee4-9852-4e66-a96d-938151d8fd3a
MacFarlane, Gary J.
e17bbdb7-9d82-42ac-8a0a-09bf10885e3c

Jones, Gareth T., Nicholl, Barbara I., McBeth, John, Davies, Kelly A., Morriss, Richard K., Dickens, Chris and MacFarlane, Gary J. (2011) Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: Results from a population-based prospective study. Arthritis Care and Research, 696-701. (doi:10.1002/acr.20417).

Record type: Article

Abstract

Objective: to determine the relationship between physically traumatic events and the onset of chronic widespread pain (CWP).

Methods: this was a case–control study nested within a large prospective cohort. CWP was determined, by questionnaire, as per the American College of Rheumatology fibromyalgia classification criteria. Data were also collected on psychological health, health behavior, and sleep problems. Participants without CWP were then followed up at 4 years, and (new-onset) CWP was determined in the same manner. At followup, participants were also asked to report whether they had experienced any of a series of physically traumatic events between baseline and followup.

Results: a total of 2,069 individuals (46.6%) participated at followup, and 241 of these individuals (11.6%) reported CWP. More than one-third of the study population reported at least 1 physically traumatic event; although these individuals were more likely to develop CWP, this relationship was completely attenuated after adjustment for confounding (odds ratio 1.01, 95% confidence interval 0.73–1.40). However, there was some evidence to suggest that involvement in a road traffic accident, specifically, may confer an increase in the risk of CWP onset.

Conclusion: this study provides support for the “at risk” phenotype hypothesis, where individuals characterized by poorer health and psychological variables may be predisposed to develop CWP following a traumatic trigger. However, although this has been seen with road traffic accidents, it is not the case with other events. Future research should examine what is peculiar about an accident, or about one's reaction to it, that confers this increase in the risk of CWP onset.

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Accepted/In Press date: 2 December 2010
e-pub ahead of print date: 6 May 2011
Published date: May 2011

Identifiers

Local EPrints ID: 491539
URI: http://eprints.soton.ac.uk/id/eprint/491539
ISSN: 0893-7524
PURE UUID: dc29a2ff-11d6-45e2-9c68-2a9e8c67fa0b
ORCID for John McBeth: ORCID iD orcid.org/0000-0001-7047-2183

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Date deposited: 25 Jun 2024 17:08
Last modified: 26 Jun 2024 02:11

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Contributors

Author: Gareth T. Jones
Author: Barbara I. Nicholl
Author: John McBeth ORCID iD
Author: Kelly A. Davies
Author: Richard K. Morriss
Author: Chris Dickens
Author: Gary J. MacFarlane

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