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Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland health survey

Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland health survey
Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland health survey

Objective: to determine whether an observation in a UK study, that persons with chronic widespread pain are at long-term increased risk of cancer mortality, can be replicated in a different setting.


Methods: subjects were participants aged ≥30 yrs in the Mini-Finland Health Survey conducted between 1979 and 1980. Information collected included prevalent pains at different joints throughout the body, demographic, anthropometric, lifestyle and occupational factors. During follow-up, until 1994, information on vital status and cause of death was obtained.


Results: 7182 persons participated (89.8%). The prevalence of widespread body pain (pain at four or more sites) was 20% in females and 12% in males, and during follow-up there were a total of 1647 deaths. The risk of death was not elevated amongst those with widespread pain [relative risk (RR): 0.86; 95% confidence interval (CI): 0.74–1.00], and in particular, those with widespread pain were at a slightly lower risk of several disease-specific causes of death and cancer death (RR: 0.64; 95% CI: 0.46–0.91).


Conclusions: this study of multiple pains has not confirmed a previous observation of an association between the reporting of widespread pain and subsequent increased risk of cancer death. Differences in the definitions used or, more probably, the population studied, in particular, a larger rural population with more multiple pains related to physical activity may account for the differences.

Cancer, Cohort study, Mortality, Widespread pain
1462-0324
805-807
Macfarlane, G.J.
e17bbdb7-9d82-42ac-8a0a-09bf10885e3c
Jones, G.T.
798952e6-fc58-4190-82d1-a6b21a189048
Knekt, P.
46c48b0e-aa8d-46cd-b1c8-3a0f0b39559b
Aromaa, A.
9496347b-49da-42f6-b083-84c390662e83
McBeth, J.
98012716-66ba-480b-9e43-ac53b51dce61
Mikkelsson, M.
f6575847-2d06-47c0-a971-67d17c1d9608
Heliovaara, M.
26fbb6f0-bd04-401a-accd-9f4e69f0199a
Macfarlane, G.J.
e17bbdb7-9d82-42ac-8a0a-09bf10885e3c
Jones, G.T.
798952e6-fc58-4190-82d1-a6b21a189048
Knekt, P.
46c48b0e-aa8d-46cd-b1c8-3a0f0b39559b
Aromaa, A.
9496347b-49da-42f6-b083-84c390662e83
McBeth, J.
98012716-66ba-480b-9e43-ac53b51dce61
Mikkelsson, M.
f6575847-2d06-47c0-a971-67d17c1d9608
Heliovaara, M.
26fbb6f0-bd04-401a-accd-9f4e69f0199a

Macfarlane, G.J., Jones, G.T., Knekt, P., Aromaa, A., McBeth, J., Mikkelsson, M. and Heliovaara, M. (2007) Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland health survey. Rheumatology, 46 (5), 805-807. (doi:10.1093/rheumatology/kel403).

Record type: Article

Abstract

Objective: to determine whether an observation in a UK study, that persons with chronic widespread pain are at long-term increased risk of cancer mortality, can be replicated in a different setting.


Methods: subjects were participants aged ≥30 yrs in the Mini-Finland Health Survey conducted between 1979 and 1980. Information collected included prevalent pains at different joints throughout the body, demographic, anthropometric, lifestyle and occupational factors. During follow-up, until 1994, information on vital status and cause of death was obtained.


Results: 7182 persons participated (89.8%). The prevalence of widespread body pain (pain at four or more sites) was 20% in females and 12% in males, and during follow-up there were a total of 1647 deaths. The risk of death was not elevated amongst those with widespread pain [relative risk (RR): 0.86; 95% confidence interval (CI): 0.74–1.00], and in particular, those with widespread pain were at a slightly lower risk of several disease-specific causes of death and cancer death (RR: 0.64; 95% CI: 0.46–0.91).


Conclusions: this study of multiple pains has not confirmed a previous observation of an association between the reporting of widespread pain and subsequent increased risk of cancer death. Differences in the definitions used or, more probably, the population studied, in particular, a larger rural population with more multiple pains related to physical activity may account for the differences.

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More information

Published date: May 2007
Keywords: Cancer, Cohort study, Mortality, Widespread pain

Identifiers

Local EPrints ID: 491816
URI: http://eprints.soton.ac.uk/id/eprint/491816
ISSN: 1462-0324
PURE UUID: 946b0eba-24a9-4fea-95f1-8128704ab542
ORCID for J. McBeth: ORCID iD orcid.org/0000-0001-7047-2183

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Date deposited: 04 Jul 2024 16:50
Last modified: 11 Jul 2024 02:18

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Contributors

Author: G.J. Macfarlane
Author: G.T. Jones
Author: P. Knekt
Author: A. Aromaa
Author: J. McBeth ORCID iD
Author: M. Mikkelsson
Author: M. Heliovaara

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