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Complex high-risk percutaneous coronary intervention types, trends, and outcomes in nonsurgical centres

Complex high-risk percutaneous coronary intervention types, trends, and outcomes in nonsurgical centres
Complex high-risk percutaneous coronary intervention types, trends, and outcomes in nonsurgical centres
Background: limited data are available on complex high-risk percutaneous coronary intervention (CHiP) trends and outcomes in nonsurgical centres (NSCs), particularly in health care systems where most centres are NSCs.

Methods: using data from a national registry, we studied the characteristics and outcomes of CHiP procedures performed for stable angina from 2006 to 2017 according to the presence or absence of on-site surgical cover. Multivariate regression analyses and propensity score matching were used to determine risks for in-hospital death, major bleeding, and major cardiovascular or cerebral events (MACCE).

Results: out of 134,730 CHiP procedures, 42,433 (31.5%) were performed in NSCs, increasing from 12.5% in 2006 to 42% in 2017. Compared with surgical centres (SCs), patients who had a CHiP procedure undertaken in NSCs were, on average, 2.4 years older and had a greater prevalence of cardiovascular risks. Common CHiP procedures performed in NSCs included poor left ventricular function (41.6%), chronic renal failure (38.8%), and chronic total occlusion percutaneous coronary intervention (31.1%). NSC-based CHiP is associated with lower odds of mortality (adjusted odds ratio [aOR] 0.7, 95% confidence interval [CI] 0.5-0.8) and major bleeding (aOR 0.7, 95% CI 0.6-0.8). In both groups, MACCE odds were similar (aOR 1.0, 95% CI 0.9-1.1).

Conclusions: CHiP numbers have steadily increased in NSCs. NSC patients were older and had a higher prevalence of cardiovascular risks than SC patients. Mortality and major bleeding odds were significantly lower in those cases undertaken in NSCs, although MACCE odds were not different between the groups.
1237-1246
Shamkhani, Warkaa
b6669a84-94ea-4b68-9033-ab42b63b9624
Rashid, Muhammad
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Moledina, Saadiq
df79c816-025c-4fb8-a3a6-60a30a14ad4b
Ludman, Peter
32dc7835-2a45-4a34-932e-bcc9dc5989b9
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Wijeysundera, Harindra C.
4febef3b-515f-4f96-bede-d881bee80f7c
Grines, Cindy L.
3331f75a-0b45-4b7b-a18d-663bb91432a9
Mamas, Mamas A.
749f1784-6654-4edb-8f6b-588da9b5ebc4
Shamkhani, Warkaa
b6669a84-94ea-4b68-9033-ab42b63b9624
Rashid, Muhammad
b08caf6c-31b2-460b-bd9b-9de85bc6bc0d
Moledina, Saadiq
df79c816-025c-4fb8-a3a6-60a30a14ad4b
Ludman, Peter
32dc7835-2a45-4a34-932e-bcc9dc5989b9
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Wijeysundera, Harindra C.
4febef3b-515f-4f96-bede-d881bee80f7c
Grines, Cindy L.
3331f75a-0b45-4b7b-a18d-663bb91432a9
Mamas, Mamas A.
749f1784-6654-4edb-8f6b-588da9b5ebc4

Shamkhani, Warkaa, Rashid, Muhammad, Moledina, Saadiq, Ludman, Peter, Curzen, Nick, Wijeysundera, Harindra C., Grines, Cindy L. and Mamas, Mamas A. (2024) Complex high-risk percutaneous coronary intervention types, trends, and outcomes in nonsurgical centres. Canadian Journal of Cardiology, 40 (7), 1237-1246. (doi:10.1016/j.cjca.2024.01.003).

Record type: Article

Abstract

Background: limited data are available on complex high-risk percutaneous coronary intervention (CHiP) trends and outcomes in nonsurgical centres (NSCs), particularly in health care systems where most centres are NSCs.

Methods: using data from a national registry, we studied the characteristics and outcomes of CHiP procedures performed for stable angina from 2006 to 2017 according to the presence or absence of on-site surgical cover. Multivariate regression analyses and propensity score matching were used to determine risks for in-hospital death, major bleeding, and major cardiovascular or cerebral events (MACCE).

Results: out of 134,730 CHiP procedures, 42,433 (31.5%) were performed in NSCs, increasing from 12.5% in 2006 to 42% in 2017. Compared with surgical centres (SCs), patients who had a CHiP procedure undertaken in NSCs were, on average, 2.4 years older and had a greater prevalence of cardiovascular risks. Common CHiP procedures performed in NSCs included poor left ventricular function (41.6%), chronic renal failure (38.8%), and chronic total occlusion percutaneous coronary intervention (31.1%). NSC-based CHiP is associated with lower odds of mortality (adjusted odds ratio [aOR] 0.7, 95% confidence interval [CI] 0.5-0.8) and major bleeding (aOR 0.7, 95% CI 0.6-0.8). In both groups, MACCE odds were similar (aOR 1.0, 95% CI 0.9-1.1).

Conclusions: CHiP numbers have steadily increased in NSCs. NSC patients were older and had a higher prevalence of cardiovascular risks than SC patients. Mortality and major bleeding odds were significantly lower in those cases undertaken in NSCs, although MACCE odds were not different between the groups.

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Accepted/In Press date: 1 January 2024
e-pub ahead of print date: 11 January 2024
Published date: 8 July 2024
Additional Information: Publisher Copyright: © 2024 The Authors

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Local EPrints ID: 492064
URI: http://eprints.soton.ac.uk/id/eprint/492064
PURE UUID: 7800d6ac-8d26-4303-8bbf-160cce6ff22f
ORCID for Nick Curzen: ORCID iD orcid.org/0000-0001-9651-7829

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Date deposited: 15 Jul 2024 16:50
Last modified: 23 Jul 2024 01:40

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Contributors

Author: Warkaa Shamkhani
Author: Muhammad Rashid
Author: Saadiq Moledina
Author: Peter Ludman
Author: Nick Curzen ORCID iD
Author: Harindra C. Wijeysundera
Author: Cindy L. Grines
Author: Mamas A. Mamas

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