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Characteristics and outcomes of patients who underwent coronary atherectomy in centers with and without on-site cardiac surgery

Characteristics and outcomes of patients who underwent coronary atherectomy in centers with and without on-site cardiac surgery
Characteristics and outcomes of patients who underwent coronary atherectomy in centers with and without on-site cardiac surgery
We aimed to describe the clinical characteristics and outcomes of patients who underwent atherectomy at the time of percutaneous coronary intervention in centers with on-site surgical centers (SCs) versus nonsurgical centers (NSCs). Patients treated with coronary atherectomy between January 1, 2006, to December 31, 2019, from the British Cardiovascular Society Intervention (BCIS) registry were included. Primary outcomes were in-hospital all-cause mortality and major adverse cardiovascular and cerebrovascular events. A total of 20,833 patients were treated with coronary atherectomy, of which 7,983 (38%) were performed at NSC. The proportion of coronary atherectomies performed in NSC increased from 12.5% in 2006 to 42% in 2019. Compared with patients treated at SC, patients treated in NSC were older (mean age 75.1 ± SD years vs 74.2 ± SD, p <0.001), but had comparable prevalence of hypertension (NSC 73.9% vs SC 72.8%, p = 0.085), diabetes mellitus (NSC 32.2% vs SC 31.6%, p = 0.43) and renal disease (NSC 6.0% vs SC 6.0%, p = 0.99). Intracoronary imaging was used more often in NSC than SC (22.3% vs 19.4%, p <0.001). After adjustment, the odds of in-hospital mortality (odds ratios [OR] 0.76, 95% confidence intervals [CI] 0.50 to 1.16), major adverse cardiovascular and cerebrovascular events (OR 0.80, 95% CI 0.53 to 1.21), emergency coronary artery bypass graft (OR 0.49, 95% CI 0.15 to 1.57), major bleeding (OR 0.67, 95% CI 0.36 to 1.24) and coronary perforation (OR 1.07, 95% CI 0.97 to 1.43) in NSC were comparable with SC. In conclusion, coronary atherectomy in hospitals with off-site surgical cover has become more frequent, with no association with poorer outcomes, compared with hospitals with on-site surgical cover.
242-248
Dafaalla, Mohamed
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Rashid, Muhammad
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Moledina, Saadiq
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Kinnaird, Tim
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Ludman, Peter
32dc7835-2a45-4a34-932e-bcc9dc5989b9
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Zaman, Sarah
1073b8eb-ba9f-4c89-99f8-76dbd3eaec96
Nolan, James
1cdb1e12-958f-4b04-a730-242dd48591b1
Dafaalla, Mohamed
967fc359-9846-47ef-9a97-db530fdc0f19
Rashid, Muhammad
077b711a-51b2-493a-a295-cb05f6bb3af8
Moledina, Saadiq
032e6c15-bd02-4354-b610-9afb936979a4
Kinnaird, Tim
c395171a-2175-4076-978f-576bada9e6aa
Ludman, Peter
32dc7835-2a45-4a34-932e-bcc9dc5989b9
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Zaman, Sarah
1073b8eb-ba9f-4c89-99f8-76dbd3eaec96
Nolan, James
1cdb1e12-958f-4b04-a730-242dd48591b1

Dafaalla, Mohamed, Rashid, Muhammad, Moledina, Saadiq, Kinnaird, Tim, Ludman, Peter, Curzen, Nick, Zaman, Sarah and Nolan, James (2023) Characteristics and outcomes of patients who underwent coronary atherectomy in centers with and without on-site cardiac surgery. American Journal of Cardiolology (Am J Cardiol), 204, 242-248. (doi:10.1016/j.amjcard.2023.07.073).

Record type: Article

Abstract

We aimed to describe the clinical characteristics and outcomes of patients who underwent atherectomy at the time of percutaneous coronary intervention in centers with on-site surgical centers (SCs) versus nonsurgical centers (NSCs). Patients treated with coronary atherectomy between January 1, 2006, to December 31, 2019, from the British Cardiovascular Society Intervention (BCIS) registry were included. Primary outcomes were in-hospital all-cause mortality and major adverse cardiovascular and cerebrovascular events. A total of 20,833 patients were treated with coronary atherectomy, of which 7,983 (38%) were performed at NSC. The proportion of coronary atherectomies performed in NSC increased from 12.5% in 2006 to 42% in 2019. Compared with patients treated at SC, patients treated in NSC were older (mean age 75.1 ± SD years vs 74.2 ± SD, p <0.001), but had comparable prevalence of hypertension (NSC 73.9% vs SC 72.8%, p = 0.085), diabetes mellitus (NSC 32.2% vs SC 31.6%, p = 0.43) and renal disease (NSC 6.0% vs SC 6.0%, p = 0.99). Intracoronary imaging was used more often in NSC than SC (22.3% vs 19.4%, p <0.001). After adjustment, the odds of in-hospital mortality (odds ratios [OR] 0.76, 95% confidence intervals [CI] 0.50 to 1.16), major adverse cardiovascular and cerebrovascular events (OR 0.80, 95% CI 0.53 to 1.21), emergency coronary artery bypass graft (OR 0.49, 95% CI 0.15 to 1.57), major bleeding (OR 0.67, 95% CI 0.36 to 1.24) and coronary perforation (OR 1.07, 95% CI 0.97 to 1.43) in NSC were comparable with SC. In conclusion, coronary atherectomy in hospitals with off-site surgical cover has become more frequent, with no association with poorer outcomes, compared with hospitals with on-site surgical cover.

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e-pub ahead of print date: 7 August 2023
Published date: 7 August 2023

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Local EPrints ID: 492136
URI: http://eprints.soton.ac.uk/id/eprint/492136
PURE UUID: e47ae090-c380-45a5-a7d2-460c67ae2085
ORCID for Nick Curzen: ORCID iD orcid.org/0000-0001-9651-7829

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Date deposited: 17 Jul 2024 16:58
Last modified: 20 Jul 2024 01:40

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Contributors

Author: Mohamed Dafaalla
Author: Muhammad Rashid
Author: Saadiq Moledina
Author: Tim Kinnaird
Author: Peter Ludman
Author: Nick Curzen ORCID iD
Author: Sarah Zaman
Author: James Nolan

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