READ ME File For 'Dataset for Doctoral Thesis, Connecting the dots: exploring the relationship between the arrangement of cortical porosity and the development of sex-specific whole bone Phenotypes in cystine string protein alpha deficient mice'

Dataset DOI: 10.5258/SOTON/D3106

ReadMe Author: Jacob Trend, University of Southampton ORCID ID 0000-0003-0394-7665

This dataset supports the thesis entitled 'Connecting the dots: exploring the relationship between the arrangement of cortical porosity and the development of sex-specific whole bone Phenotypes in cystine string protein alpha deficient mice'
AWARDED BY: Univeristy of Southampton
DATE OF AWARD: 2024

DESCRIPTION OF THE DATA
Results 1 - Chapter 3.zip
This folder contains both raw and processed cranial and tibial scans from WT and CSPa-/- mic, alongside analysis and data used during this chapter.

Results 2 - Chapter 4.zip
This folder contains both raw and processed data for synchrotorn radiation computed tomography scans of WT (C57BL6) and OcnVEGFKO murine tibia used in this thesis.

Results 3 - Chapter 5.zip
This folder contains the processed data for synchrotorn radiation computed tomography scans of WT (C57BL6) and CSPa-/- murine tibia used in this thesis. The raw data is approximately 8TB in size, and is in depulicate in Dr Clarkins office in building 85.

Results 4 - Chapter 6.zip
This folder contains the analysis supporting results chapter 6, relating the correlative assessment of bone porosity using SR CT. 

This dataset contains:
Results 1 - Chapter 3.zip
Results 2 - Chapter 4.zip
Results 3 - Chapter 5.zip
Results 4 - Chapter 6.zip

Date of data collection: 2019 - 2023

Related projects/Funders:
PhD project funded by The Gerald Kerkut Charitable Trust, and the University of Southampton.

Related publication:
Trend, Jacob, Sharma, Alisha, Michels, Lysanne, Goggin, Patricia, Schneider, Philipp, Deinhardt, Katrin, and Clarkin, Claire. Regional assessment of male murine bone exposes spatial heterogeneity in osteocyte lacunar volume associated with intracortical canals and regulation by VEGF, 2023. https://doi.org/10.1101/2023.02.08.527672.

Date that the file was created: June, 2024