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Excessive body weight in developmental coordination disorder: a systematic review and meta-analysis

Excessive body weight in developmental coordination disorder: a systematic review and meta-analysis
Excessive body weight in developmental coordination disorder: a systematic review and meta-analysis
Evidence on the link between developmental coordination disorder (DCD) and obesity and overweight is mixed. Based on a pre-registered protocol (PROSPERO: CRD42023429432), we conducted the first systematic review/meta-analysis on the association between DCD and excessive weight. Web of Science, PubMed and an institutional database aggregator were searched until the 18th of December 2023. We assessed study quality using the Newcastle-Ottawa Scale and study heterogeneity using Q and I2 statistics. Data from 22 studies were combined, comprising 11,330 individuals out of which 1861 had DCD. The main analysis showed a significant association between DCD and higher body weight (OR:1.87, 95 % CI =1.43, 2.44). Meta-regression analyses indicated that the relationship was mediated by age, with stronger effects in studies with higher mean age (p 0.004). We conclude that DCD is associated with obesity and overweight, and this association increases with age. Our study could help to implement targeted prevention and intervention measures.
0149-7634
Gambra, Leyre
7f546edb-d6de-4042-952d-a0880762ef00
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Lizoain, Pablo
d13533a8-9dea-4b64-87d4-2cbf15a7cdce
Rodriguez Romero, Diana
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Paiva, Ursula
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Gandara, Carmen
84523ec5-e0aa-4797-bf5e-d89c086c5c0b
Arrondo, Gonzalo
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Magallón, Sara
ada1177a-75d3-4ceb-8d2b-48fa0703033b
Gambra, Leyre
7f546edb-d6de-4042-952d-a0880762ef00
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Lizoain, Pablo
d13533a8-9dea-4b64-87d4-2cbf15a7cdce
Rodriguez Romero, Diana
3560f8c9-1c8f-471d-8d93-6a96d757460c
Paiva, Ursula
0ab9f662-d616-4899-997e-fd3d3509530a
Gandara, Carmen
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Arrondo, Gonzalo
5b9c1446-74f9-4dc7-aa73-6c67f3eaddbc
Magallón, Sara
ada1177a-75d3-4ceb-8d2b-48fa0703033b

Gambra, Leyre, Cortese, Samuele, Lizoain, Pablo, Rodriguez Romero, Diana, Paiva, Ursula, Gandara, Carmen, Arrondo, Gonzalo and Magallón, Sara (2024) Excessive body weight in developmental coordination disorder: a systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, 164, [105806]. (doi:10.1016/j.neubiorev.2024.105806).

Record type: Article

Abstract

Evidence on the link between developmental coordination disorder (DCD) and obesity and overweight is mixed. Based on a pre-registered protocol (PROSPERO: CRD42023429432), we conducted the first systematic review/meta-analysis on the association between DCD and excessive weight. Web of Science, PubMed and an institutional database aggregator were searched until the 18th of December 2023. We assessed study quality using the Newcastle-Ottawa Scale and study heterogeneity using Q and I2 statistics. Data from 22 studies were combined, comprising 11,330 individuals out of which 1861 had DCD. The main analysis showed a significant association between DCD and higher body weight (OR:1.87, 95 % CI =1.43, 2.44). Meta-regression analyses indicated that the relationship was mediated by age, with stronger effects in studies with higher mean age (p 0.004). We conclude that DCD is associated with obesity and overweight, and this association increases with age. Our study could help to implement targeted prevention and intervention measures.

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Accepted/In Press date: 5 July 2024
e-pub ahead of print date: 8 July 2024
Published date: 19 July 2024

Identifiers

Local EPrints ID: 492203
URI: http://eprints.soton.ac.uk/id/eprint/492203
ISSN: 0149-7634
PURE UUID: cf4b5581-1e69-4e73-9678-5daec61b90e9
ORCID for Samuele Cortese: ORCID iD orcid.org/0000-0001-5877-8075

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Date deposited: 22 Jul 2024 16:35
Last modified: 27 Jul 2024 01:47

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Contributors

Author: Leyre Gambra
Author: Samuele Cortese ORCID iD
Author: Pablo Lizoain
Author: Diana Rodriguez Romero
Author: Ursula Paiva
Author: Carmen Gandara
Author: Gonzalo Arrondo
Author: Sara Magallón

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