3D printed optofluidic biosensor: NaYF4: Yb3+, Er3+ upconversion nano-emitters for temperature sensing

Habibi, Mahsa, Bagheri, Pooya, Ghazyani, Nahid, Zare-Behtash, Hossein and Heydari, Esmaeil (2021) 3D printed optofluidic biosensor: NaYF4: Yb3+, Er3+ upconversion nano-emitters for temperature sensing. Sensors and Actuators, A: Physical, 326. (doi:10.1016/j.sna.2021.112734).

Abstract

The nonintrusive, realtime, and accurate measurement of the local temperature has applications in a variety of scenarios. This need has led to significant research to develop novel nanophotonic sensors. In this paper, a 3D-printed optofluidic chip is nano-engineered for local, contactless, and precise optical measurement of temperature in microfluidic channels using lanthanide-doped upconversion nanoparticles. Temperature sensing nano-emitters are doped in a UV-curable matrix and embedded into a microfluidic channel using maskless photolithography. Photoluminescence of NaYF4:Yb3+, Er3+ upconversion nanoparticles have two bands in the green spectrum in which the PL maximums at 521 nm and 541 nm are used for temperature sensing. Thus, enabling ratiometric temperature sensing when excited using near-infrared light, which is desirable for measurements in biological and biomedical settings. The functionality of the temperature sensor for local and nonintrusive measurements in a microalgae culture medium is demonstrated.

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Contributors

Author: Hossein Zare-Behtash

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