Global evaluation and outcomes of cholecystectomy: protocol for a multicentre, international, prospective cohort study (GlobalSurg 4)
Global evaluation and outcomes of cholecystectomy: protocol for a multicentre, international, prospective cohort study (GlobalSurg 4)
Introduction: cholecystectomy is one of the most common operations performed worldwide. Although laparoscopic surgery has been the ‘gold-standard’ approach for this operation, there is a paucity of global evidence around the variations of safe provision of cholecystectomy, including low-income and middle-income countries. This international collaborative study will allow contemporaneous data collection on the quality of cholecystectomies using measures covering infrastructure, care processes and outcomes, with the primary aim define the global variation in compliance with preoperative, intraoperative and postoperative audit standards.
Methods and analysis: Global Evaluation of Cholecystectomy Knowledge and Outcomes is a prospective, international, multicentre, observational cohort study delivered by the GlobalSurg Collaborative. Consecutive patients undergoing cholecystectomy between 31 July 2023 and 19 November 2023 will be recruited, with follow-up at 30 days and 1-year postoperatively. The study will be undertaken at any hospital providing emergency or elective surgical services for biliary disease. The primary endpoint of this study is compliance with preoperative, intraoperative and postoperative audit standards. Secondary outcomes include rates of 30-day complications, achievement of critical view of safety and rates of gallbladder cancer.
Ethics and dissemination: this project will not affect clinical practice and has been classified as clinical audit following research ethics review at University Hospital Birmingham NHS Trust. The protocol will be disseminated through the international GlobalSurg and CovidSurg network.
Cholecystectomy, Cholecystectomy, Laparoscopic, Humans, Multicenter Studies as Topic, Postoperative Complications/epidemiology, Prospective Studies, Research Design, SURGERY, Health Services Accessibility, Hepatobiliary disease
Harrison, Ewen
b1d53078-fdec-445f-a0c3-a27ffdc17c63
Kathir Kamarajah, Sivesh
01acaca2-a7fd-447c-bc77-b88e5b440cd7
Primrose, John
d85f3b28-24c6-475f-955b-ec457a3f9185
NIHR Global Health Research Unit on Global Surgery
25 July 2024
Harrison, Ewen
b1d53078-fdec-445f-a0c3-a27ffdc17c63
Kathir Kamarajah, Sivesh
01acaca2-a7fd-447c-bc77-b88e5b440cd7
Primrose, John
d85f3b28-24c6-475f-955b-ec457a3f9185
Harrison, Ewen and Kathir Kamarajah, Sivesh
,
NIHR Global Health Research Unit on Global Surgery
(2024)
Global evaluation and outcomes of cholecystectomy: protocol for a multicentre, international, prospective cohort study (GlobalSurg 4).
BMJ Open, 14 (7), [e079599].
(doi:10.1136/bmjopen-2023-079599).
Abstract
Introduction: cholecystectomy is one of the most common operations performed worldwide. Although laparoscopic surgery has been the ‘gold-standard’ approach for this operation, there is a paucity of global evidence around the variations of safe provision of cholecystectomy, including low-income and middle-income countries. This international collaborative study will allow contemporaneous data collection on the quality of cholecystectomies using measures covering infrastructure, care processes and outcomes, with the primary aim define the global variation in compliance with preoperative, intraoperative and postoperative audit standards.
Methods and analysis: Global Evaluation of Cholecystectomy Knowledge and Outcomes is a prospective, international, multicentre, observational cohort study delivered by the GlobalSurg Collaborative. Consecutive patients undergoing cholecystectomy between 31 July 2023 and 19 November 2023 will be recruited, with follow-up at 30 days and 1-year postoperatively. The study will be undertaken at any hospital providing emergency or elective surgical services for biliary disease. The primary endpoint of this study is compliance with preoperative, intraoperative and postoperative audit standards. Secondary outcomes include rates of 30-day complications, achievement of critical view of safety and rates of gallbladder cancer.
Ethics and dissemination: this project will not affect clinical practice and has been classified as clinical audit following research ethics review at University Hospital Birmingham NHS Trust. The protocol will be disseminated through the international GlobalSurg and CovidSurg network.
Text
e079599.full
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More information
Accepted/In Press date: 17 June 2024
e-pub ahead of print date: 25 July 2024
Published date: 25 July 2024
Keywords:
Cholecystectomy, Cholecystectomy, Laparoscopic, Humans, Multicenter Studies as Topic, Postoperative Complications/epidemiology, Prospective Studies, Research Design, SURGERY, Health Services Accessibility, Hepatobiliary disease
Identifiers
Local EPrints ID: 492896
URI: http://eprints.soton.ac.uk/id/eprint/492896
ISSN: 2044-6055
PURE UUID: 695bbc19-67bc-4153-91f7-e7154d8375f9
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Date deposited: 19 Aug 2024 16:49
Last modified: 20 Aug 2024 01:34
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Contributors
Author:
Ewen Harrison
Author:
Sivesh Kathir Kamarajah
Corporate Author: NIHR Global Health Research Unit on Global Surgery
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