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Computational simulation of the flow dynamic field in a porous ureteric stent

Computational simulation of the flow dynamic field in a porous ureteric stent
Computational simulation of the flow dynamic field in a porous ureteric stent

Ureteric stents are employed clinically to manage urinary obstructions or other pathological conditions. Stents made of porous and biodegradable materials have gained increasing interest, because of their excellent biocompatibility and the potential for overcoming the so-called 'forgotten stent syndrome'. However, there is very limited characterisation of their flow dynamic performance. In this study, a CFD model of the occluded and unoccluded urinary tract was developed to investigate the urinary flow dynamics in the presence of a porous ureteric stent. With increasing the permeability of the porous material (i.e., from 10-18 to 10-10 m2) both the total mass flow rate through the ureter and the average fluid velocity within the stent increased. In the unoccluded ureter, the total mass flow rate increased of 7.7% when a porous stent with permeability of 10-10 m2 was employed instead of an unporous stent. Drainage performance further improved in the presence of a ureteral occlusion, with the porous stent resulting in 10.2% greater mass flow rate compared to the unporous stent. Findings from this study provide fundamental insights into the flow performance of porous ureteric stents, with potential utility in the development pipeline of these medical devices.

Computer Simulation, Humans, Porosity, Stents, Ureter/surgery, Ureteral Obstruction
0140-0118
2373-2387
Yang, Xiaohan
ef83d2f3-47ae-4aaa-aa22-81a7a35e01fb
Mosayyebi, Ali
ab9cf6da-58c4-4441-993b-7d03d5d3549a
Carugo, Dario
760c5599-ae34-470d-966d-bc3f502734ad
Yang, Xiaohan
ef83d2f3-47ae-4aaa-aa22-81a7a35e01fb
Mosayyebi, Ali
ab9cf6da-58c4-4441-993b-7d03d5d3549a
Carugo, Dario
760c5599-ae34-470d-966d-bc3f502734ad

Yang, Xiaohan, Mosayyebi, Ali and Carugo, Dario (2022) Computational simulation of the flow dynamic field in a porous ureteric stent. Medical and Biological Engineering and Computing, 60 (8), 2373-2387. (doi:10.1007/s11517-022-02620-1).

Record type: Article

Abstract

Ureteric stents are employed clinically to manage urinary obstructions or other pathological conditions. Stents made of porous and biodegradable materials have gained increasing interest, because of their excellent biocompatibility and the potential for overcoming the so-called 'forgotten stent syndrome'. However, there is very limited characterisation of their flow dynamic performance. In this study, a CFD model of the occluded and unoccluded urinary tract was developed to investigate the urinary flow dynamics in the presence of a porous ureteric stent. With increasing the permeability of the porous material (i.e., from 10-18 to 10-10 m2) both the total mass flow rate through the ureter and the average fluid velocity within the stent increased. In the unoccluded ureter, the total mass flow rate increased of 7.7% when a porous stent with permeability of 10-10 m2 was employed instead of an unporous stent. Drainage performance further improved in the presence of a ureteral occlusion, with the porous stent resulting in 10.2% greater mass flow rate compared to the unporous stent. Findings from this study provide fundamental insights into the flow performance of porous ureteric stents, with potential utility in the development pipeline of these medical devices.

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s11517-022-02620-1 - Version of Record
Available under License Creative Commons Attribution.
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More information

Accepted/In Press date: 15 June 2022
e-pub ahead of print date: 28 June 2022
Additional Information: © 2022. The Author(s).
Keywords: Computer Simulation, Humans, Porosity, Stents, Ureter/surgery, Ureteral Obstruction

Identifiers

Local EPrints ID: 493144
URI: http://eprints.soton.ac.uk/id/eprint/493144
ISSN: 0140-0118
PURE UUID: 33aa76d0-49b4-472f-bc69-ab3d846ef28e
ORCID for Ali Mosayyebi: ORCID iD orcid.org/0000-0003-0901-6546

Catalogue record

Date deposited: 23 Aug 2024 16:54
Last modified: 21 Nov 2024 02:52

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Contributors

Author: Xiaohan Yang
Author: Ali Mosayyebi ORCID iD
Author: Dario Carugo

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