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Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register

Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register
Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register
Background and purpose: younger recipients of total hip arthroplasty (THA) highly prioritize returning to preoperative levels of physical activity (PA). Surgeons have tended to give cautious advice concerning high-impact sports participation, but there have been few long-term studies. The purpose of our study was to investigate the risk of revision arthroplasty in relation to postoperative PA levels.

Methods: patients registered in the Geneva Arthroplasty Register (GAR) who had elective THA when they were aged < 65 years were studied. Postoperative PA was collected prospectively 5-yearly using the UCLA activity scale. Cox proportional hazards models were used to estimate associations between PA and risk of revision THA.

Results: amongst 1,370 eligible subjects, median age at THA 58 years (interquartile range 51–61), UCLA scores were available for 973 (71%). During follow-up over 15 years, there were 79 revisions, giving a cumulative risk of 7.4% (95% confidence interval [CI] 5.8–9.4). After adjusting for covariates, we found an increased risk of revision for each unit increase in postoperative PA (HR 1.2, CI 1.1–1.4), and among people performing the most intensive PA (HR 2.7, CI 1.3–5.6) compared with those who were inactive.

Conclusion: the overall risk of revision was small but intensive and moderate PA may be associated with an increased risk of revision.
Humans, Arthroplasty, Replacement, Hip/adverse effects, Middle Aged, Male, Reoperation/statistics & numerical data, Female, Registries, Exercise/physiology, Risk Factors, Cohort Studies, Switzerland/epidemiology, Follow-Up Studies, Proportional Hazards Models, Prospective Studies
1745-3674
446-453
Zaballa, Elena
1b151ccc-5b1d-4edf-9549-7f604b517fcb
D'angelo, Stefania
13375ecd-1117-4b6e-99c0-32239f52eed6
Barea, Christophe
a7ea3f3e-3704-458e-879b-9f48cee10cfd
Ntani, Georgia
9b009e0a-5ab2-4c6e-a9fd-15a601e92be5
Hannouche, Didier
2bdfac8a-622e-4f03-89af-a4250ea0e8c0
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Lübbeke, Anne
838ea85d-6883-433d-bfbb-c8581185bc32
Walker-Bone, Karen
ad7d1336-ed2c-4f39-ade5-da84eb412109
Zaballa, Elena
1b151ccc-5b1d-4edf-9549-7f604b517fcb
D'angelo, Stefania
13375ecd-1117-4b6e-99c0-32239f52eed6
Barea, Christophe
a7ea3f3e-3704-458e-879b-9f48cee10cfd
Ntani, Georgia
9b009e0a-5ab2-4c6e-a9fd-15a601e92be5
Hannouche, Didier
2bdfac8a-622e-4f03-89af-a4250ea0e8c0
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Lübbeke, Anne
838ea85d-6883-433d-bfbb-c8581185bc32
Walker-Bone, Karen
ad7d1336-ed2c-4f39-ade5-da84eb412109

Zaballa, Elena, D'angelo, Stefania, Barea, Christophe, Ntani, Georgia, Hannouche, Didier, Cooper, Cyrus, Lübbeke, Anne and Walker-Bone, Karen (2024) Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register. Acta Orthopaedica, 95, 446-453. (doi:10.2340/17453674.2024.41192).

Record type: Article

Abstract

Background and purpose: younger recipients of total hip arthroplasty (THA) highly prioritize returning to preoperative levels of physical activity (PA). Surgeons have tended to give cautious advice concerning high-impact sports participation, but there have been few long-term studies. The purpose of our study was to investigate the risk of revision arthroplasty in relation to postoperative PA levels.

Methods: patients registered in the Geneva Arthroplasty Register (GAR) who had elective THA when they were aged < 65 years were studied. Postoperative PA was collected prospectively 5-yearly using the UCLA activity scale. Cox proportional hazards models were used to estimate associations between PA and risk of revision THA.

Results: amongst 1,370 eligible subjects, median age at THA 58 years (interquartile range 51–61), UCLA scores were available for 973 (71%). During follow-up over 15 years, there were 79 revisions, giving a cumulative risk of 7.4% (95% confidence interval [CI] 5.8–9.4). After adjusting for covariates, we found an increased risk of revision for each unit increase in postoperative PA (HR 1.2, CI 1.1–1.4), and among people performing the most intensive PA (HR 2.7, CI 1.3–5.6) compared with those who were inactive.

Conclusion: the overall risk of revision was small but intensive and moderate PA may be associated with an increased risk of revision.

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Accepted/In Press date: 30 June 2024
e-pub ahead of print date: 15 August 2024
Keywords: Humans, Arthroplasty, Replacement, Hip/adverse effects, Middle Aged, Male, Reoperation/statistics & numerical data, Female, Registries, Exercise/physiology, Risk Factors, Cohort Studies, Switzerland/epidemiology, Follow-Up Studies, Proportional Hazards Models, Prospective Studies

Identifiers

Local EPrints ID: 493574
URI: http://eprints.soton.ac.uk/id/eprint/493574
ISSN: 1745-3674
PURE UUID: 2e858a7b-add2-467c-92a3-f98dd2be6f08
ORCID for Stefania D'angelo: ORCID iD orcid.org/0000-0002-7267-1837
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Karen Walker-Bone: ORCID iD orcid.org/0000-0002-5992-1459

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Date deposited: 06 Sep 2024 16:47
Last modified: 07 Sep 2024 01:45

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Contributors

Author: Elena Zaballa
Author: Stefania D'angelo ORCID iD
Author: Christophe Barea
Author: Georgia Ntani
Author: Didier Hannouche
Author: Cyrus Cooper ORCID iD
Author: Anne Lübbeke

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