READ ME File For 'Next Generation SICLOPPS Screening for the Identification of inhibitors of the HIF-1a/HIF-1b protein-protein interaction'

Dataset DOI: doi.org/10.5258/SOTON/D3197

Date that the file was created: Sept, 2024

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GENERAL INFORMATION
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ReadMe Author: Ali Tavassoli, University of Southampton

Date of data collection: 2021-2024

Information about geographic location of data collection: University of Southampton, University, UK

Related projects: N/A


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SHARING/ACCESS INFORMATION
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Licenses/restrictions placed on the data, or limitations of reuse:

Recommended citation for the data:

This dataset supports the publication:
AUTHORS: Alexander McDermott, Leonie M. Windeln, Jacob S. D. Valentine, Leonardo Baldassarre, Andrew D. Foster, and Ali Tavassoli
TITLE: Next Generation SICLOPPS Screening for the Identification of inhibitors of the HIF-1HIF-1 protein-protein interaction
JOURNAL: ACS Chemical Biology
PAPER DOI: https://doi.org/10.1021/acschembio.4c00494


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DATA & FILE OVERVIEW
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This dataset contains data for the following:

Peptide hits - raw data in Microsoft Excel format
Figure 3a - raw data in Graphpad Prism format
Figure 4 a and b - raw data in Graphpad Prism format
Figure 4c - raw data in Graphpad Prism format
Figure S6 - raw data in Graphpad Prism format


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METHODOLOGICAL INFORMATION
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Description of methods used for collection/generation of data: detailed in the manuscript and its experimental section.

Methods for processing the data: KDs determined using Graphed Prism

Software- or Instrument-specific information needed to interpret the data, including software and hardware version numbers: Graphed Prism 9, Microsoft Excel

People involved with sample collection, processing, analysis and/or submission: Aexander McDermott, Leonie M. Windeln, Jacob S. D. Valentine, Leonardo Baldassarre, Andrew D. Foster