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Updated practice guideline for dual-energy X-ray absorptiometry (DXA)

Updated practice guideline for dual-energy X-ray absorptiometry (DXA)
Updated practice guideline for dual-energy X-ray absorptiometry (DXA)

The introduction of dual-energy X-ray absorptiometry (DXA) technology in the 1980s revolutionized the diagnosis, management and monitoring of osteoporosis, providing a clinical tool which is now available worldwide. However, DXA measurements are influenced by many technical factors, including the quality control procedures for the instrument, positioning of the patient, and approach to analysis. Reporting of DXA results may be confounded by factors such as selection of reference ranges for T-scores and Z-scores, as well as inadequate knowledge of current standards for interpretation. These points are addressed at length in many international guidelines but are not always easily assimilated by practising clinicians and technicians. Our aim in this report is to identify key elements pertaining to the use of DXA in clinical practice, considering both technical and clinical aspects. Here, we discuss technical aspects of DXA procedures, approaches to interpretation and integration into clinical practice, and the use of non-bone mineral density measurements, such as a vertebral fracture assessment, in clinical risk assessment.

Dual-energy X-ray absorptiometry (DXA), Practice guideline, Procedures
1619-7070
Slart, Riemer H.J.A.
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Punda, Marija
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Ali, Dalal S.
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Bazzocchi, Alberto
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Bock, Oliver
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Camacho, Pauline
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Carey, John J.
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Colquhoun, Anita
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Compston, Juliet
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Engelke, Klaus
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Erba, Paola A.
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Harvey, Nicholas C.
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Krueger, Diane
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Lems, Willem F.
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Lewiecki, E. Michael
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Morgan, Sarah
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Moseley, Kendall F.
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O'Brien, Christopher
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Probyn, Linda
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Rhee, Yumie
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Richmond, Bradford
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Schousboe, John T.
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Shuhart, Christopher
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Ward, Kate A.
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Van den Wyngaert, Tim
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Zhang-Yin, Jules
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Khan, Aliya A.
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International Working Group on DXA Best Practices
Slart, Riemer H.J.A.
23e48472-c527-45dc-8531-70d3d447b3e0
Punda, Marija
f5951c4b-d933-43af-b142-621262a04c89
Ali, Dalal S.
eec5c883-ccf3-42d5-94d9-cc0b86fa4b1d
Bazzocchi, Alberto
0be20bea-b461-4ca9-92ef-ff40cc23ea72
Bock, Oliver
decf0a49-194a-413a-ac26-faa68d4cb1e0
Camacho, Pauline
9a558206-adc0-4c4e-8ffd-8fadc271ebfa
Carey, John J.
8b52e3c5-3852-482f-a6a9-7b1be6c8d8b7
Colquhoun, Anita
abb692a6-b08e-4998-a3e4-8f33e8eb01b1
Compston, Juliet
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Engelke, Klaus
da50ea93-3761-46f0-84ed-8fe9e1c861ae
Erba, Paola A.
27908892-9817-4983-a3d7-bf37d0bc8430
Harvey, Nicholas C.
ce487fb4-d360-4aac-9d17-9466d6cba145
Krueger, Diane
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Lems, Willem F.
b4481fe4-dcb2-4baa-9f6c-72b73140efad
Lewiecki, E. Michael
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Morgan, Sarah
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Moseley, Kendall F.
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O'Brien, Christopher
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Probyn, Linda
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Rhee, Yumie
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Richmond, Bradford
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Schousboe, John T.
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Shuhart, Christopher
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Ward, Kate A.
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Van den Wyngaert, Tim
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Zhang-Yin, Jules
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Khan, Aliya A.
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Slart, Riemer H.J.A., Punda, Marija and Ali, Dalal S. , International Working Group on DXA Best Practices (2024) Updated practice guideline for dual-energy X-ray absorptiometry (DXA). European Journal of Nuclear Medicine and Molecular Imaging. (doi:10.1007/s00259-024-06912-6).

Record type: Review

Abstract

The introduction of dual-energy X-ray absorptiometry (DXA) technology in the 1980s revolutionized the diagnosis, management and monitoring of osteoporosis, providing a clinical tool which is now available worldwide. However, DXA measurements are influenced by many technical factors, including the quality control procedures for the instrument, positioning of the patient, and approach to analysis. Reporting of DXA results may be confounded by factors such as selection of reference ranges for T-scores and Z-scores, as well as inadequate knowledge of current standards for interpretation. These points are addressed at length in many international guidelines but are not always easily assimilated by practising clinicians and technicians. Our aim in this report is to identify key elements pertaining to the use of DXA in clinical practice, considering both technical and clinical aspects. Here, we discuss technical aspects of DXA procedures, approaches to interpretation and integration into clinical practice, and the use of non-bone mineral density measurements, such as a vertebral fracture assessment, in clinical risk assessment.

Text
s00259-024-06912-6 - Version of Record
Available under License Creative Commons Attribution.
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More information

Accepted/In Press date: 28 August 2024
e-pub ahead of print date: 24 September 2024
Keywords: Dual-energy X-ray absorptiometry (DXA), Practice guideline, Procedures

Identifiers

Local EPrints ID: 495158
URI: http://eprints.soton.ac.uk/id/eprint/495158
ISSN: 1619-7070
PURE UUID: ab9e24c4-4a02-426f-9ec3-06b54dd453f2
ORCID for Nicholas C. Harvey: ORCID iD orcid.org/0000-0002-8194-2512
ORCID for Kate A. Ward: ORCID iD orcid.org/0000-0001-7034-6750

Catalogue record

Date deposited: 30 Oct 2024 18:00
Last modified: 31 Oct 2024 02:47

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Contributors

Author: Riemer H.J.A. Slart
Author: Marija Punda
Author: Dalal S. Ali
Author: Alberto Bazzocchi
Author: Oliver Bock
Author: Pauline Camacho
Author: John J. Carey
Author: Anita Colquhoun
Author: Juliet Compston
Author: Klaus Engelke
Author: Paola A. Erba
Author: Diane Krueger
Author: Willem F. Lems
Author: E. Michael Lewiecki
Author: Sarah Morgan
Author: Kendall F. Moseley
Author: Christopher O'Brien
Author: Linda Probyn
Author: Yumie Rhee
Author: Bradford Richmond
Author: John T. Schousboe
Author: Christopher Shuhart
Author: Kate A. Ward ORCID iD
Author: Tim Van den Wyngaert
Author: Jules Zhang-Yin
Author: Aliya A. Khan
Corporate Author: International Working Group on DXA Best Practices

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