Clinical applications of remote ischemic preconditioning
Clinical applications of remote ischemic preconditioning
Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are responsible for a high degree of morbidity and mortality worldwide. Basic research has identified a number of interventions that stimulate innate resistance of tissues to ischemia-reperfusion injury. Here, we summarise the experimental and clinical trial data underpinning one of these “conditioning” strategies, the phenomenon of remote ischemic preconditioning.
Veighey, Kristin
2adbaf5c-141a-44bd-a7eb-faf14e0ca251
Macallister, Raymond J.
9f4b26b2-72e1-4ccf-9338-362d6193085b
14 February 2012
Veighey, Kristin
2adbaf5c-141a-44bd-a7eb-faf14e0ca251
Macallister, Raymond J.
9f4b26b2-72e1-4ccf-9338-362d6193085b
Veighey, Kristin and Macallister, Raymond J.
(2012)
Clinical applications of remote ischemic preconditioning.
Cardiology Research and Practice, 2012 (1), [620681].
(doi:10.1155/2012/620681).
Abstract
Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are responsible for a high degree of morbidity and mortality worldwide. Basic research has identified a number of interventions that stimulate innate resistance of tissues to ischemia-reperfusion injury. Here, we summarise the experimental and clinical trial data underpinning one of these “conditioning” strategies, the phenomenon of remote ischemic preconditioning.
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Cardiology Research and Practice - 2012 - Veighey - Clinical Applications of Remote Ischemic Preconditioning
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Accepted/In Press date: 29 November 2011
e-pub ahead of print date: 14 February 2012
Published date: 14 February 2012
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Local EPrints ID: 495166
URI: http://eprints.soton.ac.uk/id/eprint/495166
PURE UUID: 3410ba08-b993-4cda-a548-577942a3e517
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Date deposited: 30 Oct 2024 18:04
Last modified: 31 Oct 2024 02:55
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Author:
Raymond J. Macallister
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