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The effects of drone transportation on blood component quality: a prospective randomised controlled laboratory study

The effects of drone transportation on blood component quality: a prospective randomised controlled laboratory study
The effects of drone transportation on blood component quality: a prospective randomised controlled laboratory study
The use of uncrewed aerial vehicles (drones) has increased over the last decade. However, their application in healthcare has not been fully examined, in part, due to regulations preventing flight beyond the visual line of sight. This prospective randomised controlled laboratory study aimed to determine whether the in vitro quality of packed red blood cell components is maintained when transported by drone, beyond visual line of sight. Ten identical pairs of packed red blood cell units were randomly allocated to transport by drone or by ground vehicle (1:1, allocation concealment) 68 km between two hospitals in Northumbria, UK. Markers of blood component quality were compared at 8, 14, 28 and 35 days following blood unit manufacture. There was no statistical difference in haemolysis, potassium concentration, total haemoglobin, glucose and lactate, haematocrit and mean cell volume, between the two groups, up to the date of unit expiry. The temperature of the packed red blood cell units did not deviate outside the recommended 2-10°C for transportation, regardless of the allocated group. Blood component transport was faster by drone, but did not reach statistical significance. This study demonstrates the feasibility and safety of flying blood components by drone between hospitals in the United Kingdom.
blood transfusion, clinical transfusion medicine, haemolysis, health services research, red cells
0007-1048
2022-2030
Wiltshire, Michael
bdd56516-b907-49ff-a0c6-1c45798889a0
Boxshall, Jonathan
9e2bc609-66e6-4985-844a-d615839516d8
Milne, James
f48cfee2-73e5-46d3-9fc0-435b76a676f2
Oleniacz, Katarzyna
418a293a-ca06-4bfc-a424-e4fdceb2508c
Theobald, Katherine
2c1196be-b9f6-4c75-8552-5af1c12a6997
Phillips, Benedict
b4781b99-1b1a-49cf-aadb-551116725710
Wiltshire, Michael
bdd56516-b907-49ff-a0c6-1c45798889a0
Boxshall, Jonathan
9e2bc609-66e6-4985-844a-d615839516d8
Milne, James
f48cfee2-73e5-46d3-9fc0-435b76a676f2
Oleniacz, Katarzyna
418a293a-ca06-4bfc-a424-e4fdceb2508c
Theobald, Katherine
2c1196be-b9f6-4c75-8552-5af1c12a6997
Phillips, Benedict
b4781b99-1b1a-49cf-aadb-551116725710

Wiltshire, Michael, Boxshall, Jonathan, Milne, James, Oleniacz, Katarzyna, Theobald, Katherine and Phillips, Benedict (2024) The effects of drone transportation on blood component quality: a prospective randomised controlled laboratory study. British Journal of Haematology, 205 (5), 2022-2030. (doi:10.1111/bjh.19666).

Record type: Article

Abstract

The use of uncrewed aerial vehicles (drones) has increased over the last decade. However, their application in healthcare has not been fully examined, in part, due to regulations preventing flight beyond the visual line of sight. This prospective randomised controlled laboratory study aimed to determine whether the in vitro quality of packed red blood cell components is maintained when transported by drone, beyond visual line of sight. Ten identical pairs of packed red blood cell units were randomly allocated to transport by drone or by ground vehicle (1:1, allocation concealment) 68 km between two hospitals in Northumbria, UK. Markers of blood component quality were compared at 8, 14, 28 and 35 days following blood unit manufacture. There was no statistical difference in haemolysis, potassium concentration, total haemoglobin, glucose and lactate, haematocrit and mean cell volume, between the two groups, up to the date of unit expiry. The temperature of the packed red blood cell units did not deviate outside the recommended 2-10°C for transportation, regardless of the allocated group. Blood component transport was faster by drone, but did not reach statistical significance. This study demonstrates the feasibility and safety of flying blood components by drone between hospitals in the United Kingdom.

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More information

Accepted/In Press date: 11 July 2024
e-pub ahead of print date: 8 August 2024
Keywords: blood transfusion, clinical transfusion medicine, haemolysis, health services research, red cells

Identifiers

Local EPrints ID: 496492
URI: http://eprints.soton.ac.uk/id/eprint/496492
ISSN: 0007-1048
PURE UUID: 668d7f3f-7de8-4ed6-bc6d-0392b74b1f04
ORCID for Katherine Theobald: ORCID iD orcid.org/0000-0003-2158-5346

Catalogue record

Date deposited: 17 Dec 2024 17:33
Last modified: 18 Dec 2024 03:12

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Contributors

Author: Michael Wiltshire
Author: Jonathan Boxshall
Author: James Milne
Author: Katarzyna Oleniacz
Author: Katherine Theobald ORCID iD
Author: Benedict Phillips

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