Method and apparatus for obtaining chemical and/or material specific information of a sample using light scattered by Rayleigh scattering and/or Raman
Method and apparatus for obtaining chemical and/or material specific information of a sample using light scattered by Rayleigh scattering and/or Raman
Two images of a sample 300 are obtained. Each image indicates the intensity of Rayleigh scattered light 203 i) for incident light 201 of a different wavelength, or ii) for incident light 201 of a different polarisation state, or iii) of scattered light 203 of a different polarisation state. Alternatively, each image indicates the intensity of Raman scattered light 203 i) of a different wavelength, or ii) for incident light 201 of a different polarisation state, or iii) for incident light 201 of a different polarisation state. Chemical and/or material specific information of the sample 300 is determined based on the change in intensity of the scattered light 203 in dependence on the change in wavelength and/or polarisation of the incident and/or scattered light. The determination step may involve a look-up table, direct calculation, classification via e.g. principal component analysis or a neural network. Light sheet microscopy may be used.
GB 2592081 A
Intellectual Property Office
18 August 2021
Mahajan, Sumeet
b131f40a-479e-4432-b662-19d60d4069e9
Hanrahan, Niall
df8a0edc-a5bd-4979-aa6f-0ea1bff159c3
Bourdakos, Konstaninos
4a6d4e96-0c1c-46d0-9095-828c33a6be04
Lane, Simon
8e80111f-5012-4950-a228-dfb8fb9df52d
Mahajan, Sumeet, Hanrahan, Niall, Bourdakos, Konstaninos and Lane, Simon
(Inventors)
(2021)
Method and apparatus for obtaining chemical and/or material specific information of a sample using light scattered by Rayleigh scattering and/or Raman.
GB 2592081 A.
Abstract
Two images of a sample 300 are obtained. Each image indicates the intensity of Rayleigh scattered light 203 i) for incident light 201 of a different wavelength, or ii) for incident light 201 of a different polarisation state, or iii) of scattered light 203 of a different polarisation state. Alternatively, each image indicates the intensity of Raman scattered light 203 i) of a different wavelength, or ii) for incident light 201 of a different polarisation state, or iii) for incident light 201 of a different polarisation state. Chemical and/or material specific information of the sample 300 is determined based on the change in intensity of the scattered light 203 in dependence on the change in wavelength and/or polarisation of the incident and/or scattered light. The determination step may involve a look-up table, direct calculation, classification via e.g. principal component analysis or a neural network. Light sheet microscopy may be used.
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Published date: 18 August 2021
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Local EPrints ID: 496618
URI: http://eprints.soton.ac.uk/id/eprint/496618
PURE UUID: 0a835bbc-8cff-46be-ba0e-47ac7353c1cc
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Date deposited: 07 Jan 2025 18:38
Last modified: 10 Jan 2025 03:09
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Contributors
Inventor:
Niall Hanrahan
Inventor:
Konstaninos Bourdakos
Inventor:
Simon Lane
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