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Osteoporosis and rheumatoid arthritis: A review of current understanding and practice

Osteoporosis and rheumatoid arthritis: A review of current understanding and practice
Osteoporosis and rheumatoid arthritis: A review of current understanding and practice
This review presents a current perspective on the association between rheumatoid arthritis (RA) and osteoporosis. Many factors contribute to the increased risk of osteoporosis and fracture in RA patients. These factors include advanced age, duration of disease, long-term glucocorticoid use, and poor inflammation control inflammation in RA. This review discusses current guidelines and their limitations in assessing bone health in RA-related osteoporosis. Available anti-osteoporotic treatments, their mechanisms of action, and their potential benefits in managing the interaction between RA and osteoporosis are discussed. We also consider potential advancements, including areas of future development in RA and osteoporosis diagnosis and management.
disease control, glucocorticoid-induced osteoporosis, osteoporotic fracture, rheumatoid arthritis fracture, rheumatoid arthritis mortality
1750-8460
1-11
Kirkham-Wilson, Fiona
2926698a-6fc2-471d-bf15-8ff6428f893c
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Kirkham-Wilson, Fiona
2926698a-6fc2-471d-bf15-8ff6428f893c
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1

Kirkham-Wilson, Fiona and Dennison, Elaine (2024) Osteoporosis and rheumatoid arthritis: A review of current understanding and practice. British Journal of Hospital Medicine, 85 (11), 1-11. (doi:10.12968/hmed.2024.0341).

Record type: Review

Abstract

This review presents a current perspective on the association between rheumatoid arthritis (RA) and osteoporosis. Many factors contribute to the increased risk of osteoporosis and fracture in RA patients. These factors include advanced age, duration of disease, long-term glucocorticoid use, and poor inflammation control inflammation in RA. This review discusses current guidelines and their limitations in assessing bone health in RA-related osteoporosis. Available anti-osteoporotic treatments, their mechanisms of action, and their potential benefits in managing the interaction between RA and osteoporosis are discussed. We also consider potential advancements, including areas of future development in RA and osteoporosis diagnosis and management.

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e-pub ahead of print date: 13 November 2024
Published date: 30 November 2024
Additional Information: Publisher Copyright: © 2024 The Author(s).
Keywords: disease control, glucocorticoid-induced osteoporosis, osteoporotic fracture, rheumatoid arthritis fracture, rheumatoid arthritis mortality

Identifiers

Local EPrints ID: 496660
URI: http://eprints.soton.ac.uk/id/eprint/496660
ISSN: 1750-8460
PURE UUID: 8477a993-7ac7-475d-a043-9c4b075a0a7d
ORCID for Elaine Dennison: ORCID iD orcid.org/0000-0002-3048-4961

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Date deposited: 07 Jan 2025 18:55
Last modified: 10 Jan 2025 02:36

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Contributors

Author: Fiona Kirkham-Wilson
Author: Elaine Dennison ORCID iD

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