From NAFPD to MAFPD: implications of a nomenclature change
From NAFPD to MAFPD: implications of a nomenclature change
Background and objective: obesity is a global health issue closely linked to multiple cardiovascular and metabolic conditions. The renaming of nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction associated fatty liver disease (MAFLD) has sparked discussions about renaming nonalcoholic fatty pancreas disease (NAFPD). This narrative review explores the potential benefits and challenges of renaming NAFPD to metabolic dysfunction-associated fatty pancreas disease (MAFPD) and its potential clinical implications.
Methods: the review employs a narrative approach, synthesizing existing literature and expert opinions to evaluate the rationale behind and the possible implications of renaming NAFPD to MAFPD.
Key Content and Findings: NAFPD is increasingly recognized worldwide but lacks standardized diagnostic criteria, hindering its independent classification as a disease. Renaming NAFPD to MAFPD may enhance diagnostic accuracy, prognostic prediction, and personalized treatment strategies. It may also facilitate global epidemiological research, data sharing, and collaboration. Major challenges include establishing uniform diagnostic guidelines for promoting and educating about the newly proposed terminology.
Conclusions: the proposed renaming from NAFPD to MAFPD may offer promising benefits despite challenges. It may also lead to improved management and understanding of the disease, potentially benefiting global healthcare strategies aimed at addressing obesity-related pancreatic complications
Zheng, Wen
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Liu, Wen-Yue
574dccc6-f921-49c9-88fc-5c89376dc2c8
Lou, Wenhui
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Targher, Giovanni
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Byrne, Chrisopher D.
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Hegyi, Péter
c1b3da45-ea31-461c-aecd-511319c001f5
Eslam, Mohammed
52de581d-5eb2-4d19-b29d-0ed6d2d0deb1
George, Jacob
779a411a-14c1-4049-a867-92a98f109b64
Zheng, Ming-Hua
916f7560-c0d7-46d9-8540-55d80d1f9752
Zheng, Wen
4d1185e6-2ece-4e95-b8d7-6d6b79b0ce1d
Liu, Wen-Yue
574dccc6-f921-49c9-88fc-5c89376dc2c8
Lou, Wenhui
3168784b-b3a4-40cd-9015-b12fd9e34391
Targher, Giovanni
31b4b4d3-6e97-407f-9247-09e7b26a97cc
Byrne, Chrisopher D.
1370b997-cead-4229-83a7-53301ed2a43c
Hegyi, Péter
c1b3da45-ea31-461c-aecd-511319c001f5
Eslam, Mohammed
52de581d-5eb2-4d19-b29d-0ed6d2d0deb1
George, Jacob
779a411a-14c1-4049-a867-92a98f109b64
Zheng, Ming-Hua
916f7560-c0d7-46d9-8540-55d80d1f9752
Zheng, Wen, Liu, Wen-Yue, Lou, Wenhui, Targher, Giovanni, Byrne, Chrisopher D., Hegyi, Péter, Eslam, Mohammed, George, Jacob and Zheng, Ming-Hua
(2024)
From NAFPD to MAFPD: implications of a nomenclature change.
Hepatobiliary Surgery and Nutrition.
(doi:10.21037/hbsn-24-284).
Abstract
Background and objective: obesity is a global health issue closely linked to multiple cardiovascular and metabolic conditions. The renaming of nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction associated fatty liver disease (MAFLD) has sparked discussions about renaming nonalcoholic fatty pancreas disease (NAFPD). This narrative review explores the potential benefits and challenges of renaming NAFPD to metabolic dysfunction-associated fatty pancreas disease (MAFPD) and its potential clinical implications.
Methods: the review employs a narrative approach, synthesizing existing literature and expert opinions to evaluate the rationale behind and the possible implications of renaming NAFPD to MAFPD.
Key Content and Findings: NAFPD is increasingly recognized worldwide but lacks standardized diagnostic criteria, hindering its independent classification as a disease. Renaming NAFPD to MAFPD may enhance diagnostic accuracy, prognostic prediction, and personalized treatment strategies. It may also facilitate global epidemiological research, data sharing, and collaboration. Major challenges include establishing uniform diagnostic guidelines for promoting and educating about the newly proposed terminology.
Conclusions: the proposed renaming from NAFPD to MAFPD may offer promising benefits despite challenges. It may also lead to improved management and understanding of the disease, potentially benefiting global healthcare strategies aimed at addressing obesity-related pancreatic complications
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Accepted/In Press date: 10 August 2024
e-pub ahead of print date: 18 November 2024
Identifiers
Local EPrints ID: 496893
URI: http://eprints.soton.ac.uk/id/eprint/496893
ISSN: 2304-3881
PURE UUID: 6a31e4d1-e552-4c43-a56d-3968df68153d
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Date deposited: 08 Jan 2025 11:40
Last modified: 21 Aug 2025 01:46
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Author:
Wen Zheng
Author:
Wen-Yue Liu
Author:
Wenhui Lou
Author:
Giovanni Targher
Author:
Péter Hegyi
Author:
Mohammed Eslam
Author:
Jacob George
Author:
Ming-Hua Zheng
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