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Application of additively manufactured 3D scaffolds for bone cancer treatment: a review

Application of additively manufactured 3D scaffolds for bone cancer treatment: a review
Application of additively manufactured 3D scaffolds for bone cancer treatment: a review
Bone cancer is a critical health problem on a global scale, and the associated huge clinical and economic burdens are still rising. Although many clinical approaches are currently used for bone cancer treatment, these methods usually affect the normal body functions and thus present significant limitations. Meanwhile, advanced materials and additive manufacturing have opened up promising avenues for the development of new strategies targeting both bone cancer treatment and post-treatment bone regeneration. This paper presents a comprehensive review of bone cancer and its current treatment methods, particularly focusing on a number of advanced strategies such as scaffolds based on advanced functional materials, drug-loaded scaffolds, and scaffolds for photothermal/magnetothermal therapy. Finally, the main research challenges and future perspectives are elaborated.
2096-5524
556-579
Hou, Yanhao
082d81da-35ae-4632-8e53-94a6b3a2fe99
Wang, Weiguang
0cc699c0-e7b3-49d0-8c84-1e9d63f747d8
Bartolo, Paulo
2c085472-871d-4ac1-8767-23e5fe9703cf
Hou, Yanhao
082d81da-35ae-4632-8e53-94a6b3a2fe99
Wang, Weiguang
0cc699c0-e7b3-49d0-8c84-1e9d63f747d8
Bartolo, Paulo
2c085472-871d-4ac1-8767-23e5fe9703cf

Hou, Yanhao, Wang, Weiguang and Bartolo, Paulo (2022) Application of additively manufactured 3D scaffolds for bone cancer treatment: a review. Bio-Design and Manufacturing, 5, 556-579. (doi:10.1007/s42242-022-00182-7).

Record type: Article

Abstract

Bone cancer is a critical health problem on a global scale, and the associated huge clinical and economic burdens are still rising. Although many clinical approaches are currently used for bone cancer treatment, these methods usually affect the normal body functions and thus present significant limitations. Meanwhile, advanced materials and additive manufacturing have opened up promising avenues for the development of new strategies targeting both bone cancer treatment and post-treatment bone regeneration. This paper presents a comprehensive review of bone cancer and its current treatment methods, particularly focusing on a number of advanced strategies such as scaffolds based on advanced functional materials, drug-loaded scaffolds, and scaffolds for photothermal/magnetothermal therapy. Finally, the main research challenges and future perspectives are elaborated.

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Accepted/In Press date: 28 December 2021
Published date: 7 March 2022

Identifiers

Local EPrints ID: 497787
URI: http://eprints.soton.ac.uk/id/eprint/497787
ISSN: 2096-5524
PURE UUID: 5cd9d090-456a-420b-abe5-11fe20b21467
ORCID for Weiguang Wang: ORCID iD orcid.org/0000-0002-8959-329X

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Date deposited: 31 Jan 2025 17:39
Last modified: 01 Feb 2025 03:20

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Contributors

Author: Yanhao Hou
Author: Weiguang Wang ORCID iD
Author: Paulo Bartolo

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