Extending the field-of-view of speckle-based microtomography with the UMPA model

Savatović, Sara, De Marco, Fabio, Riedel, Mirko, Laundon, Davis J., Regner, Michèle Louise, Hammel, Jörg U., Lewis, Rohan M., Herzen, Julia and Thibault, Pierre (2024) Extending the field-of-view of speckle-based microtomography with the UMPA model. Muller, Bert and Wang, Ge (eds.) In Developments in X-Ray Tomography XV. vol. 13152, SPIE. 10 pp . (doi:10.1117/12.3027762).

Abstract

Phase-contrast computed tomography enables the visualization of weakly-absorbing samples with high contrast. Speckle-based imaging (SBI) is a phase-sensitive X-ray imaging technique that requires the use of a wavefront marker (typically a sandpaper) to retrieve multi-modal information: absorption, refraction and scattering. These quantities are derived by analyzing the distortions in a reference pattern generated when the sample is inserted into the beam. The Unified Modulated Pattern Analysis (UMPA) model is a speckle-tracking method capable of processing such datasets. While high-resolution tomographic reconstructions can be achieved at the synchrotron, there is usually a trade-off with sample dimensions. Here, we use UMPA with a multi-frame approach for signal retrieval, enabling the expansion of the reconstructed field-of-view (FOV) by moving the sample instead of the modulator transversely to the beam. We demonstrate this technique on a human placental tissue sample.

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Contributors

Author: Davis J. Laundon

Author: Rohan M. Lewis

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