Mass spectrometric analysis in combinatorial chemistry
Mass spectrometric analysis in combinatorial chemistry
The continuing success of the combinatorial approach is heavily reliant on analytical methodologies, which allow for the rapid and accurate characterisation of medicinally relevant molecules from compound libraries. Mass spectrometry has recently been touted as the most suitable tool for a range of combinatorial applications such as structural elucidation and screening. The refinement of conventional methods, developments of techniques such as Fourier transform ion cyclotron resonance and new screening methodologies have allowed the medicinal chemist to tackle the growing analytical challenges posed by combinatorial chemistry.
337-341
Swali, Vinay
2ca9c286-6e21-4ae7-95bc-755cda3f9ef2
Langley, G. John
7ac80d61-b91d-4261-ad17-255f94ea21ea
Bradley, Mark
562b9add-34c4-4620-bfa1-c7c83a0f0900
19 June 1999
Swali, Vinay
2ca9c286-6e21-4ae7-95bc-755cda3f9ef2
Langley, G. John
7ac80d61-b91d-4261-ad17-255f94ea21ea
Bradley, Mark
562b9add-34c4-4620-bfa1-c7c83a0f0900
Swali, Vinay, Langley, G. John and Bradley, Mark
(1999)
Mass spectrometric analysis in combinatorial chemistry.
Current Opinion in Chemical Biology, 3 (3), .
(doi:10.1016/S1367-5931(99)80050-7).
Abstract
The continuing success of the combinatorial approach is heavily reliant on analytical methodologies, which allow for the rapid and accurate characterisation of medicinally relevant molecules from compound libraries. Mass spectrometry has recently been touted as the most suitable tool for a range of combinatorial applications such as structural elucidation and screening. The refinement of conventional methods, developments of techniques such as Fourier transform ion cyclotron resonance and new screening methodologies have allowed the medicinal chemist to tackle the growing analytical challenges posed by combinatorial chemistry.
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Published date: 19 June 1999
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Local EPrints ID: 498597
URI: http://eprints.soton.ac.uk/id/eprint/498597
ISSN: 1367-5931
PURE UUID: e43d4ac4-8bcb-4b20-b603-917639f4c8c0
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Date deposited: 21 Feb 2025 18:01
Last modified: 22 Feb 2025 02:34
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Author:
Vinay Swali
Author:
Mark Bradley
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