Integrating clinical history with allergy tests
Integrating clinical history with allergy tests
To make an accurate diagnosis of food allergy, the patient's clinical history needs to be integrated with their IgE-sensitization test results and, where necessary, an oral food challenge. For many patients, skin, prick testing or specific IgE to whole allergens will be the only tests required. Where the diagnosis is still unclear, specific IgE to allergen components or, where available Basophil Activation Testing or Mast cell Activation Tests may be helpful. For some patients it will be necessary to undertake a food challenge test to family rule out or make a diagnosis of food allergy. In this article, we look at how the clinical presentation can be integrated with the IgE-sensitization test results to arrive at an accurate diagnosis of food allergy.
Allergen components, Basophil activation testing, Clinical history IgE-sensitization test, Diagnosis, Food allergy, Mast cell activation tests, Oral food challenge, Skin prick testing, Specific IgE testing
657-667
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
21 June 2024
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Roberts, Graham
(2024)
Integrating clinical history with allergy tests.
In,
Sicherer, Scott H.
(ed.)
Encyclopedia of Food Allergy.
1 ed.
Elsevier, .
(doi:10.1016/B978-0-323-96018-2.00082-1).
Record type:
Book Section
Abstract
To make an accurate diagnosis of food allergy, the patient's clinical history needs to be integrated with their IgE-sensitization test results and, where necessary, an oral food challenge. For many patients, skin, prick testing or specific IgE to whole allergens will be the only tests required. Where the diagnosis is still unclear, specific IgE to allergen components or, where available Basophil Activation Testing or Mast cell Activation Tests may be helpful. For some patients it will be necessary to undertake a food challenge test to family rule out or make a diagnosis of food allergy. In this article, we look at how the clinical presentation can be integrated with the IgE-sensitization test results to arrive at an accurate diagnosis of food allergy.
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Published date: 21 June 2024
Keywords:
Allergen components, Basophil activation testing, Clinical history IgE-sensitization test, Diagnosis, Food allergy, Mast cell activation tests, Oral food challenge, Skin prick testing, Specific IgE testing
Identifiers
Local EPrints ID: 498740
URI: http://eprints.soton.ac.uk/id/eprint/498740
PURE UUID: dd94cc5e-ee98-48cc-9fe7-4e467233fc12
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Date deposited: 26 Feb 2025 17:31
Last modified: 27 Feb 2025 02:39
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Editor:
Scott H. Sicherer
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