Carbon dot-decorated polystyrene microspheres for whispering-gallery mode biosensing
Carbon dot-decorated polystyrene microspheres for whispering-gallery mode biosensing
Whispering gallery mode (WGM) resonators doped with fluorescent materials find impressive applications in biological sensing. They do not require special conditions for the excitation of WGM inside that provide the basis for in vivo sensing. Currently, the problem of materials for in vivo WGM sensors are substantial since their fluorescence should have stable optical properties as well as they should be biocompatible. To address this we present WGM microresonators of 5–7 (Formula presented.) m, where the dopant is made of carbon quantum dots (CDs). CDs are biocompatible since they are produced from carbon and demonstrate bright optical emission, which shows different bands depending on the excitation wavelength. The WGM sensors developed here were tested as label-free biosensors by detecting bovine serum albumin molecules. The results showed WGM frequency shifting, with the limit of detection down to (Formula presented.) M level.
biosensing, bovine serum albumin, carbon dots, microsphere, whispering gallery modes
Starovoytov, Anton A.
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Soloveva, Evgeniia O.
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Kurassova, Kamilla
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Bogdanov, Kirill V.
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Arefina, Irina A.
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Shevchenko, Natalia N.
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Vartanyan, Tigran A.
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Dadadzhanov, Daler R.
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Toropov, Nikita A.
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20 May 2024
Starovoytov, Anton A.
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Soloveva, Evgeniia O.
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Kurassova, Kamilla
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Bogdanov, Kirill V.
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Arefina, Irina A.
61ba2379-8c48-443e-86b9-89b45cf7917f
Shevchenko, Natalia N.
3ae1d426-121c-45d9-a906-f91701569b39
Vartanyan, Tigran A.
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Dadadzhanov, Daler R.
486129e3-78b2-4b86-a37f-1d6b5640e6af
Toropov, Nikita A.
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Starovoytov, Anton A., Soloveva, Evgeniia O., Kurassova, Kamilla, Bogdanov, Kirill V., Arefina, Irina A., Shevchenko, Natalia N., Vartanyan, Tigran A., Dadadzhanov, Daler R. and Toropov, Nikita A.
(2024)
Carbon dot-decorated polystyrene microspheres for whispering-gallery mode biosensing.
Photonics, 11 (5), [480].
(doi:10.3390/photonics11050480).
Abstract
Whispering gallery mode (WGM) resonators doped with fluorescent materials find impressive applications in biological sensing. They do not require special conditions for the excitation of WGM inside that provide the basis for in vivo sensing. Currently, the problem of materials for in vivo WGM sensors are substantial since their fluorescence should have stable optical properties as well as they should be biocompatible. To address this we present WGM microresonators of 5–7 (Formula presented.) m, where the dopant is made of carbon quantum dots (CDs). CDs are biocompatible since they are produced from carbon and demonstrate bright optical emission, which shows different bands depending on the excitation wavelength. The WGM sensors developed here were tested as label-free biosensors by detecting bovine serum albumin molecules. The results showed WGM frequency shifting, with the limit of detection down to (Formula presented.) M level.
Text
photonics-11-00480
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More information
Accepted/In Press date: 10 May 2024
Published date: 20 May 2024
Keywords:
biosensing, bovine serum albumin, carbon dots, microsphere, whispering gallery modes
Identifiers
Local EPrints ID: 499333
URI: http://eprints.soton.ac.uk/id/eprint/499333
ISSN: 2304-6732
PURE UUID: d3190ffd-859b-4186-b829-bc5311dec95b
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Date deposited: 17 Mar 2025 17:38
Last modified: 22 Aug 2025 02:38
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Contributors
Author:
Anton A. Starovoytov
Author:
Evgeniia O. Soloveva
Author:
Kamilla Kurassova
Author:
Kirill V. Bogdanov
Author:
Irina A. Arefina
Author:
Natalia N. Shevchenko
Author:
Tigran A. Vartanyan
Author:
Daler R. Dadadzhanov
Author:
Nikita A. Toropov
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