The University of Southampton
University of Southampton Institutional Repository

Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level

Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level
Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level
Background: forecasting healthcare demand is essential in epidemic settings, both to inform situational awareness and facilitate resource planning. Ideally, forecasts should be robust across time and locations. During the COVID-19 pandemic in England, it is an ongoing concern that demand for hospital care for COVID-19 patients in England will exceed available resources.

Methods: we made weekly forecasts of daily COVID-19 hospital admissions for National Health Service (NHS) Trusts in England between August 2020 and April 2021 using three disease-agnostic forecasting models: a mean ensemble of autoregressive time series models, a linear regression model with 7-day-lagged local cases as a predictor, and a scaled convolution of local cases and a delay distribution. We compared their point and probabilistic accuracy to a mean-ensemble of them all and to a simple baseline model of no change from the last day of admissions. We measured predictive performance using the weighted interval score (WIS) and considered how this changed in different scenarios (the length of the predictive horizon, the date on which the forecast was made, and by location), as well as how much admissions forecasts improved when future cases were known.

Results: all models outperformed the baseline in the majority of scenarios. Forecasting accuracy varied by forecast date and location, depending on the trajectory of the outbreak, and all individual models had instances where they were the top- or bottom-ranked model. Forecasts produced by the mean-ensemble were both the most accurate and most consistently accurate forecasts amongst all the models considered. Forecasting accuracy was improved when using future observed, rather than forecast, cases, especially at longer forecast horizons.

Conclusions: assuming no change in current admissions is rarely better than including at least a trend. Using confirmed COVID-19 cases as a predictor can improve admissions forecasts in some scenarios, but this is variable and depends on the ability to make consistently good case forecasts. However, ensemble forecasts can make forecasts that make consistently more accurate forecasts across time and locations. Given minimal requirements on data and computation, our admissions forecasting ensemble could be used to anticipate healthcare needs in future epidemic or pandemic settings.
1741-7015
Meakin, Sophie
3d336cd9-8fb9-4e8d-bc52-d1daf73d97b8
Abbott, Sam
e8d25152-b481-40b4-b429-82c93d21c26e
Bosse, Nikos
994b2bac-1481-4444-ad57-b885ccf032ef
Munday, James
1291e7de-1489-46be-a9e2-84b4984c120d
Gruson, Hugo
730be5f7-b562-4a3b-82c0-ec905a2e73e3
Hellewell, Joel
e2203422-4e86-4de4-8768-55e969275030
Sherratt, Katharine
bf00a77d-7057-4fe2-95c5-e9d928557eda
Chapman, Lloyd A.C.
4c7ad8dd-ae52-4c1e-bb49-f1f49b6e460d
Prem, Kiesha
f444dbda-ab2b-4f0e-bf1b-f3bfb709aa38
Klepac, Petra
c0c57afb-f2f5-4675-a18b-e5a0d5ee0c7b
Jombart, Thibaut
7144327d-cb18-44cf-9765-509b98f6435b
Knight, Gwenan M.
264364d8-dd24-497c-af7e-bc046901f744
Jafari, Yalda
54e9870d-ba49-49ce-a9b7-0d0e19708f14
Flasche, Stefan
3499af0a-c722-4ae2-90ba-4ce6401389f5
Waites, William
a069e5ff-f440-4b89-ae81-3b58c2ae2afd
Jit, Mark
c99d1e17-a445-4ac7-8b56-ba179ebf5190
Eggo, Rosalind M.
150c61b4-762d-4356-9924-1cdb75126db6
Villabona-Arenas, C. Julian
7f9bf4ba-045d-4c8e-928e-ad8f5670b069
Russell, Timothy W.
461139c6-6cb1-4289-8aba-7f09f1bd6c0a
Medley, Graham
6cb3010d-7d2b-4bc9-b8c1-b4d9ce031372
Edmunds, W. John
478db96b-7b72-416e-82b1-6ce9f0f8c8c2
Davies, Nicholas G.
25184305-5278-41d4-9654-8da0ca1cf51d
Liu, Yang
e5a70a94-9912-442e-b66e-b2fef86266cc
Hué, Stéphane
49f3897a-9fba-4693-a216-09307eaa718f
Brady, Oliver
2acbd374-26d3-4e56-9e19-558eef1d4f9b
Pung, Rachael
ce2d32be-f67b-412c-bf9b-1b275472b2a4
Abbas, Kaja
43cf5abc-77b4-4aea-809d-b9b4f0e48b17
Gimma, Amy
642070ad-36eb-41e6-8cd8-8c1bd7397afc
Mee, Paul
6bd96e3d-8560-4c55-9f32-5326c32c16e6
Endo, Akira
24b58000-1eff-4fa8-a64a-b3cd9a727314
Clifford, Samuel
fa51f8cb-b11b-4099-a994-2a0c96eb1e0f
Sun, Fiona Yueqian
155d0f1b-452c-416c-83b2-11f9b72d25b3
McCarthy, Ciara V.
6c1cab5b-e570-401c-9ede-869384d5f4e4
Quilty, Billy J.
7fc8c6b4-2740-45d6-96b1-70a0553cf339
Rosello, Alicia
18be3a96-acab-4888-900f-ef3865226340
Sandmann, Frank G.
26136dce-a8e7-434e-86a6-79f810bd8302
Barnard, Rosanna C.
e2d26b50-3e89-4970-917b-86be72ab922e
Kucharski, Adam J.
19975425-144e-4e68-9bcd-25e50cc7ad31
Procter, Simon R.
ac6bc704-455f-4801-afe5-4a01b6475e95
Jarvis, Christopher I.
c8c1f5a6-e077-4d0e-b79f-d12e21bac3c0
Gibbs, Hamish P.
a7c68116-c71c-4df2-87c3-2f209f1f203e
Hodgson, David
88a5730e-ab5a-4b38-88ac-9c39dd96ad55
Lowe, Rachel
8b9eb87e-6ef9-452c-b5dc-650cc467da12
Atkins, Katherine E.
e396359b-6346-44fc-be90-41824d4050ea
Koltai, Mihaly
64cea1ba-ac4c-46d0-a57e-7a0f0d45677d
Pearson, Carl A.B.
b9f67ec0-ab59-4537-9aa5-45eb62f8e523
Finch, Emilie
178db10b-0dca-43f8-bc47-1b0156adf9ab
Wong, Kerry L.M.
84ba7d11-429f-4b16-9f0c-8ed790514316
Quaife, Matthew
f6139761-9d82-4a81-b2ef-e750977ab8f4
CMMID COVID-19 Working Group
Meakin, Sophie
3d336cd9-8fb9-4e8d-bc52-d1daf73d97b8
Abbott, Sam
e8d25152-b481-40b4-b429-82c93d21c26e
Bosse, Nikos
994b2bac-1481-4444-ad57-b885ccf032ef
Munday, James
1291e7de-1489-46be-a9e2-84b4984c120d
Gruson, Hugo
730be5f7-b562-4a3b-82c0-ec905a2e73e3
Hellewell, Joel
e2203422-4e86-4de4-8768-55e969275030
Sherratt, Katharine
bf00a77d-7057-4fe2-95c5-e9d928557eda
Chapman, Lloyd A.C.
4c7ad8dd-ae52-4c1e-bb49-f1f49b6e460d
Prem, Kiesha
f444dbda-ab2b-4f0e-bf1b-f3bfb709aa38
Klepac, Petra
c0c57afb-f2f5-4675-a18b-e5a0d5ee0c7b
Jombart, Thibaut
7144327d-cb18-44cf-9765-509b98f6435b
Knight, Gwenan M.
264364d8-dd24-497c-af7e-bc046901f744
Jafari, Yalda
54e9870d-ba49-49ce-a9b7-0d0e19708f14
Flasche, Stefan
3499af0a-c722-4ae2-90ba-4ce6401389f5
Waites, William
a069e5ff-f440-4b89-ae81-3b58c2ae2afd
Jit, Mark
c99d1e17-a445-4ac7-8b56-ba179ebf5190
Eggo, Rosalind M.
150c61b4-762d-4356-9924-1cdb75126db6
Villabona-Arenas, C. Julian
7f9bf4ba-045d-4c8e-928e-ad8f5670b069
Russell, Timothy W.
461139c6-6cb1-4289-8aba-7f09f1bd6c0a
Medley, Graham
6cb3010d-7d2b-4bc9-b8c1-b4d9ce031372
Edmunds, W. John
478db96b-7b72-416e-82b1-6ce9f0f8c8c2
Davies, Nicholas G.
25184305-5278-41d4-9654-8da0ca1cf51d
Liu, Yang
e5a70a94-9912-442e-b66e-b2fef86266cc
Hué, Stéphane
49f3897a-9fba-4693-a216-09307eaa718f
Brady, Oliver
2acbd374-26d3-4e56-9e19-558eef1d4f9b
Pung, Rachael
ce2d32be-f67b-412c-bf9b-1b275472b2a4
Abbas, Kaja
43cf5abc-77b4-4aea-809d-b9b4f0e48b17
Gimma, Amy
642070ad-36eb-41e6-8cd8-8c1bd7397afc
Mee, Paul
6bd96e3d-8560-4c55-9f32-5326c32c16e6
Endo, Akira
24b58000-1eff-4fa8-a64a-b3cd9a727314
Clifford, Samuel
fa51f8cb-b11b-4099-a994-2a0c96eb1e0f
Sun, Fiona Yueqian
155d0f1b-452c-416c-83b2-11f9b72d25b3
McCarthy, Ciara V.
6c1cab5b-e570-401c-9ede-869384d5f4e4
Quilty, Billy J.
7fc8c6b4-2740-45d6-96b1-70a0553cf339
Rosello, Alicia
18be3a96-acab-4888-900f-ef3865226340
Sandmann, Frank G.
26136dce-a8e7-434e-86a6-79f810bd8302
Barnard, Rosanna C.
e2d26b50-3e89-4970-917b-86be72ab922e
Kucharski, Adam J.
19975425-144e-4e68-9bcd-25e50cc7ad31
Procter, Simon R.
ac6bc704-455f-4801-afe5-4a01b6475e95
Jarvis, Christopher I.
c8c1f5a6-e077-4d0e-b79f-d12e21bac3c0
Gibbs, Hamish P.
a7c68116-c71c-4df2-87c3-2f209f1f203e
Hodgson, David
88a5730e-ab5a-4b38-88ac-9c39dd96ad55
Lowe, Rachel
8b9eb87e-6ef9-452c-b5dc-650cc467da12
Atkins, Katherine E.
e396359b-6346-44fc-be90-41824d4050ea
Koltai, Mihaly
64cea1ba-ac4c-46d0-a57e-7a0f0d45677d
Pearson, Carl A.B.
b9f67ec0-ab59-4537-9aa5-45eb62f8e523
Finch, Emilie
178db10b-0dca-43f8-bc47-1b0156adf9ab
Wong, Kerry L.M.
84ba7d11-429f-4b16-9f0c-8ed790514316
Quaife, Matthew
f6139761-9d82-4a81-b2ef-e750977ab8f4

Meakin, Sophie, Abbott, Sam, Bosse, Nikos, Munday, James, Gruson, Hugo, Hellewell, Joel and Sherratt, Katharine , CMMID COVID-19 Working Group (2022) Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level. BMC Medicine, 20, [86]. (doi:10.1186/s12916-022-02271-x).

Record type: Article

Abstract

Background: forecasting healthcare demand is essential in epidemic settings, both to inform situational awareness and facilitate resource planning. Ideally, forecasts should be robust across time and locations. During the COVID-19 pandemic in England, it is an ongoing concern that demand for hospital care for COVID-19 patients in England will exceed available resources.

Methods: we made weekly forecasts of daily COVID-19 hospital admissions for National Health Service (NHS) Trusts in England between August 2020 and April 2021 using three disease-agnostic forecasting models: a mean ensemble of autoregressive time series models, a linear regression model with 7-day-lagged local cases as a predictor, and a scaled convolution of local cases and a delay distribution. We compared their point and probabilistic accuracy to a mean-ensemble of them all and to a simple baseline model of no change from the last day of admissions. We measured predictive performance using the weighted interval score (WIS) and considered how this changed in different scenarios (the length of the predictive horizon, the date on which the forecast was made, and by location), as well as how much admissions forecasts improved when future cases were known.

Results: all models outperformed the baseline in the majority of scenarios. Forecasting accuracy varied by forecast date and location, depending on the trajectory of the outbreak, and all individual models had instances where they were the top- or bottom-ranked model. Forecasts produced by the mean-ensemble were both the most accurate and most consistently accurate forecasts amongst all the models considered. Forecasting accuracy was improved when using future observed, rather than forecast, cases, especially at longer forecast horizons.

Conclusions: assuming no change in current admissions is rarely better than including at least a trend. Using confirmed COVID-19 cases as a predictor can improve admissions forecasts in some scenarios, but this is variable and depends on the ability to make consistently good case forecasts. However, ensemble forecasts can make forecasts that make consistently more accurate forecasts across time and locations. Given minimal requirements on data and computation, our admissions forecasting ensemble could be used to anticipate healthcare needs in future epidemic or pandemic settings.

Text
s12916-022-02271-x - Version of Record
Available under License Creative Commons Attribution.
Download (3MB)

More information

Accepted/In Press date: 20 January 2022
Published date: 21 February 2022

Identifiers

Local EPrints ID: 500146
URI: http://eprints.soton.ac.uk/id/eprint/500146
ISSN: 1741-7015
PURE UUID: 9989a6c4-3d04-4a90-b656-697772d00078
ORCID for William Waites: ORCID iD orcid.org/0000-0002-7759-6805

Catalogue record

Date deposited: 22 Apr 2025 16:30
Last modified: 22 Aug 2025 02:43

Export record

Altmetrics

Contributors

Author: Sophie Meakin
Author: Sam Abbott
Author: Nikos Bosse
Author: James Munday
Author: Hugo Gruson
Author: Joel Hellewell
Author: Katharine Sherratt
Author: Lloyd A.C. Chapman
Author: Kiesha Prem
Author: Petra Klepac
Author: Thibaut Jombart
Author: Gwenan M. Knight
Author: Yalda Jafari
Author: Stefan Flasche
Author: William Waites ORCID iD
Author: Mark Jit
Author: Rosalind M. Eggo
Author: C. Julian Villabona-Arenas
Author: Timothy W. Russell
Author: Graham Medley
Author: W. John Edmunds
Author: Nicholas G. Davies
Author: Yang Liu
Author: Stéphane Hué
Author: Oliver Brady
Author: Rachael Pung
Author: Kaja Abbas
Author: Amy Gimma
Author: Paul Mee
Author: Akira Endo
Author: Samuel Clifford
Author: Fiona Yueqian Sun
Author: Ciara V. McCarthy
Author: Billy J. Quilty
Author: Alicia Rosello
Author: Frank G. Sandmann
Author: Rosanna C. Barnard
Author: Adam J. Kucharski
Author: Simon R. Procter
Author: Christopher I. Jarvis
Author: Hamish P. Gibbs
Author: David Hodgson
Author: Rachel Lowe
Author: Katherine E. Atkins
Author: Mihaly Koltai
Author: Carl A.B. Pearson
Author: Emilie Finch
Author: Kerry L.M. Wong
Author: Matthew Quaife
Corporate Author: CMMID COVID-19 Working Group

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×