Laser-induced fabrication of doped-graphene based on collagen for bone tissue engineering scaffold applications

Wang, Weiguang, Huang, Yihe, Hou, Yanhao, Meng, Duo, Pan, Kewen, Bartolo, Paulo and Li, Lin (2024) Laser-induced fabrication of doped-graphene based on collagen for bone tissue engineering scaffold applications. CIRP Annals, 73 (1), 165-168. (doi:10.1016/j.cirp.2024.04.018).

Abstract

Electro-active scaffolds play an important role in bone tissue engineering applications, serving as physical substrates for cell proliferation and osteogenic differentiation, ultimately realizing new bone regeneration. This paper discusses a novel strategy to synthesize graphene through laser-induced surface doping, using bone collagen as the carbon source, serving as a key functional filler to be combined with biocompatible, biodegradable poly(ε-caprolactone) (PCL), for the fabrication of the next generation electro-active bone tissue engineering scaffolds. Scaffolds are fabricated through material-extrusion additive manufacturing. The developed graphene is proven to present a significant enhancement effect on surface and mechanical properties over the conventional graphene material.

This record has no associated files available for download.

Contributors

Author: Weiguang Wang

Download statistics