The University of Southampton
×
Filter your search:
University of Southampton Institutional Repository

WO2025133630 - Antigen binding proteins

WO2025133630 - Antigen binding proteins
WO2025133630 - Antigen binding proteins
The present invention relates to a novel antigen binding protein comprising at least two CH1 domains, wherein the at least two CH1 domains comprise a cysteine residue at an amino acid position corresponding to position 222 according to Kabat numbering of human IgG1 CH1 domain. The invention further provides related nucleic acids, expression vectors, and host cells. The present invention also provides pharmaceutical compositions comprising said antigen binding protein. Finally, the invention also provides a method for increasing the activity of antigen binding protein.
WO/2025/133630
Tews, Ivo
9117fc5e-d01c-4f8d-a734-5b14d3eee8dd
Cragg, Mark
ec97f80e-f3c8-49b7-a960-20dff648b78c
Essex, Jonathan W.
1f409cfe-6ba4-42e2-a0ab-a931826314b5

Tews, Ivo, Cragg, Mark and Essex, Jonathan W. (Inventors) (2025) WO2025133630 - Antigen binding proteins. WO/2025/133630.

Record type: Patent

Abstract

The present invention relates to a novel antigen binding protein comprising at least two CH1 domains, wherein the at least two CH1 domains comprise a cysteine residue at an amino acid position corresponding to position 222 according to Kabat numbering of human IgG1 CH1 domain. The invention further provides related nucleic acids, expression vectors, and host cells. The present invention also provides pharmaceutical compositions comprising said antigen binding protein. Finally, the invention also provides a method for increasing the activity of antigen binding protein.

This record has no associated files available for download.

More information

Published date: 26 June 2025
Related URLs:

Identifiers

Local EPrints ID: 503948
URI: http://eprints.soton.ac.uk/id/eprint/503948
PURE UUID: 5b526da2-8bd4-4bb1-a363-773ffbfa1829
ORCID for Ivo Tews: ORCID iD orcid.org/0000-0002-4704-1139
ORCID for Mark Cragg: ORCID iD orcid.org/0000-0003-2077-089X
ORCID for Jonathan W. Essex: ORCID iD orcid.org/0000-0003-2639-2746

Catalogue record

Date deposited: 19 Aug 2025 16:31
Last modified: 20 Aug 2025 01:46

Export record

Contributors

Inventor: Ivo Tews ORCID iD
Inventor: Mark Cragg ORCID iD
Inventor: Jonathan W. Essex ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×