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Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder.

Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder.
Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder.
In this retrospective study, we investigated potential correlations between PSD volume, brain structure volumes, and clinical severity scales in young children with ASD. We employed a Deep Learning based approach to extract PSD volume from 3D-T2 Fluid Attenuated Inversion Recovery sequences. PSD volumes did not change with age but was significantly correlated with extra-axial CSF volume and severity of developmental delay.
pediatric, autism spectrum disorder, MRI
University of Southampton
Agarwal, Nivedita
8dffa34e-17c9-4858-93f9-e3b93915ddda
Rizzato, Gloria
43641ffb-68ca-4997-9079-58fed53f7763
Peruzzo, Denis
1662a7c7-d885-46a6-bf17-d3d72916a96c
Agarwal, Nivedita
8dffa34e-17c9-4858-93f9-e3b93915ddda
Rizzato, Gloria
43641ffb-68ca-4997-9079-58fed53f7763
Peruzzo, Denis
1662a7c7-d885-46a6-bf17-d3d72916a96c

Agarwal, Nivedita (2025) Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder. University of Southampton doi:10.6084/m9.figshare.24582369.v4 [Dataset]

Record type: Dataset

Abstract

In this retrospective study, we investigated potential correlations between PSD volume, brain structure volumes, and clinical severity scales in young children with ASD. We employed a Deep Learning based approach to extract PSD volume from 3D-T2 Fluid Attenuated Inversion Recovery sequences. PSD volumes did not change with age but was significantly correlated with extra-axial CSF volume and severity of developmental delay.

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Published date: 27 August 2025
Keywords: pediatric, autism spectrum disorder, MRI

Identifiers

Local EPrints ID: 504407
URI: http://eprints.soton.ac.uk/id/eprint/504407
PURE UUID: ceed2e9d-9d8c-4886-8ebb-3e1800f5a330
ORCID for Nivedita Agarwal: ORCID iD orcid.org/0000-0002-1387-9566

Catalogue record

Date deposited: 08 Sep 2025 17:10
Last modified: 16 Apr 2026 02:02

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Contributors

Creator: Nivedita Agarwal ORCID iD
Contributor: Gloria Rizzato
Contributor: Denis Peruzzo

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