Barriers and solutions for global access to osteoporosis management: a Position Paper from the International Osteoporosis Foundation
Barriers and solutions for global access to osteoporosis management: a Position Paper from the International Osteoporosis Foundation
Our ability to optimally manage bone health across the lifecourse, and so minimise the risk of fractures, has advanced substantially in recent decades. Whilst fractures and osteoporosis in older age were historically viewed simply as inherent in normal ageing, they are now recognised as manifestations of age-related disease. Key to advancing the field was the development of conceptual (relating to impaired bone mass and microarchitecture with increased propensity to fracture), and subsequent World Health Organization densitometric definitions of osteoporosis, cementing the role of dual-energy X-ray absorptiometry in bone health management. However, whilst low bone mineral density is a strong risk factor for fracture, many individuals who do fracture have normal or only modestly reduced bone mineral density. Furthermore, the existence of two definitions constituting a condition called "osteoporosis", one based on a measurement, and the other conceptual, has led to uncertainty in clinical practice. The field is therefore moving towards calculation of an individual's absolute fracture risk, based on clinical risk factors, with the option to incorporate bone mineral density (if available) as a risk factor rather than as an indication for treatment. Uptake of this new direction has been variable internationally, with many parts of the world, particularly low- and middle-income countries, still predicating treatment (where osteoporosis services exist) on bone mineral density, despite poor availability of densitometry in many such settings. In this Position Paper, on behalf of the International Osteoporosis Foundation, we review the current barriers which prevent equitable access to optimal bone health management worldwide and recommend potential solutions which might be implemented to overcome them.
Access, Bone health, Epidemiology, Inequity, Management, Osteoporosis
1495-1507
Harvey, Nicholas C.
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Al-Daghri, Nasser
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Beaudart, Charlotte
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Brandi, Maria Luisa
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Burlet, Nansa
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Campusano, Claudia
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Cavalier, Etienne
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Chandran, Manju
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Cooper, Cyrus
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Dawson-Hughes, Bess
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Halbout, Philippe
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Hough, Teréza
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Lazaretti-Castro, Marise
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Matijevic, Radmila
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Mithal, Ambrish
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Njeze, Ngozi
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Rizzoli, René
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Saleh, Yousef
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Kanis, John A.
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Ward, Kate
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McCloskey, Eugene
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September 2025
Harvey, Nicholas C.
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Al-Daghri, Nasser
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Beaudart, Charlotte
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Brandi, Maria Luisa
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Burlet, Nansa
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Campusano, Claudia
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Cavalier, Etienne
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Chandran, Manju
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Cooper, Cyrus
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Dawson-Hughes, Bess
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Halbout, Philippe
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Hough, Teréza
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Lazaretti-Castro, Marise
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Matijevic, Radmila
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Mithal, Ambrish
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Njeze, Ngozi
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Rizzoli, René
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Saleh, Yousef
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Kanis, John A.
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Ward, Kate
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McCloskey, Eugene
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Harvey, Nicholas C., Al-Daghri, Nasser, Beaudart, Charlotte, Brandi, Maria Luisa, Burlet, Nansa, Campusano, Claudia, Cavalier, Etienne, Chandran, Manju, Cooper, Cyrus, Dawson-Hughes, Bess, Halbout, Philippe, Hough, Teréza, Lazaretti-Castro, Marise, Matijevic, Radmila, Mithal, Ambrish, Njeze, Ngozi, Rizzoli, René, Saleh, Yousef, Kanis, John A., Ward, Kate and McCloskey, Eugene
(2025)
Barriers and solutions for global access to osteoporosis management: a Position Paper from the International Osteoporosis Foundation.
Osteoporosis International, 36 (9), .
(doi:10.1007/s00198-025-07628-5).
Abstract
Our ability to optimally manage bone health across the lifecourse, and so minimise the risk of fractures, has advanced substantially in recent decades. Whilst fractures and osteoporosis in older age were historically viewed simply as inherent in normal ageing, they are now recognised as manifestations of age-related disease. Key to advancing the field was the development of conceptual (relating to impaired bone mass and microarchitecture with increased propensity to fracture), and subsequent World Health Organization densitometric definitions of osteoporosis, cementing the role of dual-energy X-ray absorptiometry in bone health management. However, whilst low bone mineral density is a strong risk factor for fracture, many individuals who do fracture have normal or only modestly reduced bone mineral density. Furthermore, the existence of two definitions constituting a condition called "osteoporosis", one based on a measurement, and the other conceptual, has led to uncertainty in clinical practice. The field is therefore moving towards calculation of an individual's absolute fracture risk, based on clinical risk factors, with the option to incorporate bone mineral density (if available) as a risk factor rather than as an indication for treatment. Uptake of this new direction has been variable internationally, with many parts of the world, particularly low- and middle-income countries, still predicating treatment (where osteoporosis services exist) on bone mineral density, despite poor availability of densitometry in many such settings. In this Position Paper, on behalf of the International Osteoporosis Foundation, we review the current barriers which prevent equitable access to optimal bone health management worldwide and recommend potential solutions which might be implemented to overcome them.
Text
s00198-025-07628-5
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Accepted/In Press date: 10 July 2025
e-pub ahead of print date: 22 August 2025
Published date: September 2025
Keywords:
Access, Bone health, Epidemiology, Inequity, Management, Osteoporosis
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Local EPrints ID: 505678
URI: http://eprints.soton.ac.uk/id/eprint/505678
ISSN: 0937-941X
PURE UUID: e4b3923f-997a-427b-a136-e7e16e612aac
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Date deposited: 16 Oct 2025 16:37
Last modified: 18 Oct 2025 01:50
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Contributors
Author:
Nasser Al-Daghri
Author:
Charlotte Beaudart
Author:
Maria Luisa Brandi
Author:
Nansa Burlet
Author:
Claudia Campusano
Author:
Etienne Cavalier
Author:
Manju Chandran
Author:
Bess Dawson-Hughes
Author:
Philippe Halbout
Author:
Teréza Hough
Author:
Marise Lazaretti-Castro
Author:
Radmila Matijevic
Author:
Ambrish Mithal
Author:
Ngozi Njeze
Author:
René Rizzoli
Author:
Yousef Saleh
Author:
John A. Kanis
Author:
Eugene McCloskey
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