Optimising a digital mindfulness-based intervention to reduce risk factors for disordered eating: a Multiphase Optimisation Strategy (MOST) Feasibility Trial
Optimising a digital mindfulness-based intervention to reduce risk factors for disordered eating: a Multiphase Optimisation Strategy (MOST) Feasibility Trial
Objective: mindfulness-based interventions (MBIs) show promise in reducing risk factors for disordered eating. Digital delivery offers scalable reach, but effects vary and engagement is generally suboptimal—potentially due to the length, complexity, and variation in content. Identifying the most effective and engaging components is necessary to streamline interventions. Guided by the multiphase optimization strategy (MOST), this study assessed the feasibility of a factorial trial to evaluate whether including emotion regulation (ER) and self-compassion (SC) enhances the effects of decentred awareness and acceptance (DA + A, observing thoughts and feelings as separate from the self) in a digital MBI.
Method: a 2 × 2 factorial design tested four intervention conditions. Each included DA + A content, with or without added ER and/or SC. Participants (N = 92, M = 21.1 years, range = 18–32) were randomized and given 3-weeks' access. Feasibility outcomes included recruitment, retention, data analysis, engagement, and acceptability. Intervention outcomes—weight and shape concerns, negative affect, mindfulness, ER, and SC—were assessed at baseline, postintervention, and 1-month follow-up.
Results: recruitment exceeded targets. Retention was acceptable (58% completed postintervention and 59% follow-up assessments). All planned analyses for the main trial were feasible. Engagement met preregistered criteria (77%–85% completed Module 1 across ER and SC conditions; mean of four modules). Acceptability was high (M = 4.28/5). Participants valued reminders and provided design suggestions.
Discussion: findings support progression to a fully powered optimization trial. This study demonstrates that MOST can be embedded within a pilot study, providing a foundation to develop more effective, engaging, and scalable interventions.
Osborne, Emma L.
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Ainsworth, Ben
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Hooper, Nic
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Chadwick, Paul
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Atkinson, Melissa J.
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Osborne, Emma L.
778546ca-0509-4975-87f2-50e1692eee53
Ainsworth, Ben
b02d78c3-aa8b-462d-a534-31f1bf164f81
Hooper, Nic
2d7f1bf2-bdb9-4bf8-bb5c-53e64fce0e12
Chadwick, Paul
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Atkinson, Melissa J.
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Osborne, Emma L., Ainsworth, Ben, Hooper, Nic, Chadwick, Paul and Atkinson, Melissa J.
(2025)
Optimising a digital mindfulness-based intervention to reduce risk factors for disordered eating: a Multiphase Optimisation Strategy (MOST) Feasibility Trial.
International Journal of Eating Disorders.
(doi:10.1002/eat.24546).
Abstract
Objective: mindfulness-based interventions (MBIs) show promise in reducing risk factors for disordered eating. Digital delivery offers scalable reach, but effects vary and engagement is generally suboptimal—potentially due to the length, complexity, and variation in content. Identifying the most effective and engaging components is necessary to streamline interventions. Guided by the multiphase optimization strategy (MOST), this study assessed the feasibility of a factorial trial to evaluate whether including emotion regulation (ER) and self-compassion (SC) enhances the effects of decentred awareness and acceptance (DA + A, observing thoughts and feelings as separate from the self) in a digital MBI.
Method: a 2 × 2 factorial design tested four intervention conditions. Each included DA + A content, with or without added ER and/or SC. Participants (N = 92, M = 21.1 years, range = 18–32) were randomized and given 3-weeks' access. Feasibility outcomes included recruitment, retention, data analysis, engagement, and acceptability. Intervention outcomes—weight and shape concerns, negative affect, mindfulness, ER, and SC—were assessed at baseline, postintervention, and 1-month follow-up.
Results: recruitment exceeded targets. Retention was acceptable (58% completed postintervention and 59% follow-up assessments). All planned analyses for the main trial were feasible. Engagement met preregistered criteria (77%–85% completed Module 1 across ER and SC conditions; mean of four modules). Acceptability was high (M = 4.28/5). Participants valued reminders and provided design suggestions.
Discussion: findings support progression to a fully powered optimization trial. This study demonstrates that MOST can be embedded within a pilot study, providing a foundation to develop more effective, engaging, and scalable interventions.
Text
Osborne et al. 2025_IJED Accepted Manuscript_MOST Feasibility Trial
- Accepted Manuscript
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Intl J Eating Disorders - 2025 - Osborne - Optimizing a Digital Mindfulness‐Based Intervention to Reduce Risk Factors for
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Accepted/In Press date: 4 September 2025
e-pub ahead of print date: 16 September 2025
Identifiers
Local EPrints ID: 505737
URI: http://eprints.soton.ac.uk/id/eprint/505737
ISSN: 0276-3478
PURE UUID: 92020863-3a13-4cec-b80a-ca97bbf9d22d
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Date deposited: 17 Oct 2025 16:34
Last modified: 18 Oct 2025 01:44
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Contributors
Author:
Emma L. Osborne
Author:
Ben Ainsworth
Author:
Nic Hooper
Author:
Paul Chadwick
Author:
Melissa J. Atkinson
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