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Dysautonomia causing severe orthostatic hypotension: an important, early finding in neurodegenerative disorders

Dysautonomia causing severe orthostatic hypotension: an important, early finding in neurodegenerative disorders
Dysautonomia causing severe orthostatic hypotension: an important, early finding in neurodegenerative disorders

Orthostatic hypotension is common and dangerous; it has neurogenic and nonneurogenic causes. We present the case of a 40-year-old man with severe neurogenic hypotension, caused by young-onset multiple system atrophy. In patients presenting with neurogenic orthostatic hypotension, underlying neurodegenerative diseases should always be considered. (Level of Difficulty: Advanced.).

2666-0849
1156-1160
Lovegrove, Elizabeth
d7b61630-099a-4faf-94a8-10506cc9887c
Rull, Gurvinder
5a1c30a1-f140-4601-8ecd-76b9a1c59316
Shah, Mussadiq
6bcc67e4-3899-4ee6-a901-15599e96b61e
Julu, Peter O
87fa5377-dc3f-46dd-bbd7-e53600961a1a
Wolff, Christopher
4c52a464-c9de-476b-80a4-6129486ba802
Gallagher, David A
6e7fe5e5-3d5d-493e-9b94-200e42ac9df2
Lobo, Melvin D
015aa592-76b8-4f62-ba27-d2261e005085
Lovegrove, Elizabeth
d7b61630-099a-4faf-94a8-10506cc9887c
Rull, Gurvinder
5a1c30a1-f140-4601-8ecd-76b9a1c59316
Shah, Mussadiq
6bcc67e4-3899-4ee6-a901-15599e96b61e
Julu, Peter O
87fa5377-dc3f-46dd-bbd7-e53600961a1a
Wolff, Christopher
4c52a464-c9de-476b-80a4-6129486ba802
Gallagher, David A
6e7fe5e5-3d5d-493e-9b94-200e42ac9df2
Lobo, Melvin D
015aa592-76b8-4f62-ba27-d2261e005085

Lovegrove, Elizabeth, Rull, Gurvinder, Shah, Mussadiq, Julu, Peter O, Wolff, Christopher, Gallagher, David A and Lobo, Melvin D (2021) Dysautonomia causing severe orthostatic hypotension: an important, early finding in neurodegenerative disorders. JACC. Case Reports, 3 (8), 1156-1160. (doi:10.1016/j.jaccas.2021.03.006).

Record type: Article

Abstract

Orthostatic hypotension is common and dangerous; it has neurogenic and nonneurogenic causes. We present the case of a 40-year-old man with severe neurogenic hypotension, caused by young-onset multiple system atrophy. In patients presenting with neurogenic orthostatic hypotension, underlying neurodegenerative diseases should always be considered. (Level of Difficulty: Advanced.).

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Published date: 21 July 2021
Additional Information: © 2021 The Authors.

Identifiers

Local EPrints ID: 505900
URI: http://eprints.soton.ac.uk/id/eprint/505900
DOI: doi:10.1016/j.jaccas.2021.03.006
ISSN: 2666-0849
PURE UUID: d1b177ee-c11a-424f-8be3-9fc01bd84d77
ORCID for Elizabeth Lovegrove: ORCID iD orcid.org/0000-0003-0393-4266

Catalogue record

Date deposited: 22 Oct 2025 16:58
Last modified: 23 Oct 2025 02:15

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Contributors

Author: Elizabeth Lovegrove ORCID iD
Author: Gurvinder Rull
Author: Mussadiq Shah
Author: Peter O Julu
Author: Christopher Wolff
Author: David A Gallagher
Author: Melvin D Lobo

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