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The 2022 symposium on dementia and brain aging in low- and middle-income countries: highlights on research, diagnosis, care, and impact

The 2022 symposium on dementia and brain aging in low- and middle-income countries: highlights on research, diagnosis, care, and impact
The 2022 symposium on dementia and brain aging in low- and middle-income countries: highlights on research, diagnosis, care, and impact

Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. HIGHLIGHTS: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.

Humans, Dementia/diagnosis, Developing Countries, Aging, Brain, Congresses as Topic, Biomedical Research
1552-5260
4290-4314
Kalaria, Raj
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Maestre, Gladys
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Mahinrad, Simin
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Carrillo, Maria C.
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Gbessemehlan, Antoine
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Hornberger, Michael
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Ihara, Masafumi
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et al.
Kalaria, Raj
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Maestre, Gladys
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Mahinrad, Simin
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Arshad, Faheem
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Babalola, David Oluwasayo
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Bak, Thomas H.
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Bellaj, Tarek
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Carrillo, Maria C.
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Celestin, Kaputu-Kalala-Malu
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Damasceno, Albertino
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de Silva, Ranil Karunamuni
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de Silva, Rohan
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Djibuti, Mamuka
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Grinberg, Lea T.
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Hogervorst, Eef
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Hornberger, Michael
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Ihara, Masafumi
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Issac, Thomas Gregor
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Jönsson, Linus
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Karanja, Wambui M.
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Lee, Joseph H.
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Leroi, Iracema
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Livingston, Gill
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Mbakile-Mahlanza, Lingani
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Miller, Bruce L.
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Musyimi, Christine Wayua
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Mutiso, Victoria N.
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Nakasujja, Noeline
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Ndetei, David M.
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Nightingale, Sam
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Novotni, Gabriela
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Kalaria, Raj, Maestre, Gladys and Mahinrad, Simin , et al. (2024) The 2022 symposium on dementia and brain aging in low- and middle-income countries: highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia, 20 (6), 4290-4314. (doi:10.1002/alz.13836).

Record type: Review

Abstract

Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. HIGHLIGHTS: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.

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Alzheimer s Dementia - 2024 - Kalaria - The 2022 symposium on dementia and brain aging in low‐ and middle‐income - Version of Record
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Accepted/In Press date: 28 February 2024
e-pub ahead of print date: 2 May 2024
Published date: 16 June 2024
Keywords: Humans, Dementia/diagnosis, Developing Countries, Aging, Brain, Congresses as Topic, Biomedical Research

Identifiers

Local EPrints ID: 506487
URI: http://eprints.soton.ac.uk/id/eprint/506487
ISSN: 1552-5260
PURE UUID: d9ca16fa-07b2-4059-be8c-75bf03e150a2
ORCID for Michael Hornberger: ORCID iD orcid.org/0000-0002-2214-3788

Catalogue record

Date deposited: 10 Nov 2025 17:38
Last modified: 11 Nov 2025 03:10

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Contributors

Author: Raj Kalaria
Author: Gladys Maestre
Author: Simin Mahinrad
Author: Daisy M. Acosta
Author: Rufus Olusola Akinyemi
Author: Suvarna Alladi
Author: Ricardo F. Allegri
Author: Faheem Arshad
Author: David Oluwasayo Babalola
Author: Olusegun Baiyewu
Author: Thomas H. Bak
Author: Tarek Bellaj
Author: David K. Brodie-Mends
Author: Maria C. Carrillo
Author: Kaputu-Kalala-Malu Celestin
Author: Albertino Damasceno
Author: Ranil Karunamuni de Silva
Author: Rohan de Silva
Author: Mamuka Djibuti
Author: Anna Jane Dreyer
Author: Ratnavalli Ellajosyula
Author: Temitope H. Farombi
Author: Robert P. Friedland
Author: Noe Garza
Author: Antoine Gbessemehlan
Author: Eliza Eleni-Zacharoula Georgiou
Author: Ishtar Govia
Author: Lea T. Grinberg
Author: Maëlenn Guerchet
Author: Seid Ali Gugssa
Author: Joy Louise Gumikiriza-Onoria
Author: Eef Hogervorst
Author: Michael Hornberger ORCID iD
Author: Agustin Ibanez
Author: Masafumi Ihara
Author: Thomas Gregor Issac
Author: Linus Jönsson
Author: Wambui M. Karanja
Author: Joseph H. Lee
Author: Iracema Leroi
Author: Gill Livingston
Author: Facundo Francisco Manes
Author: Lingani Mbakile-Mahlanza
Author: Bruce L. Miller
Author: Christine Wayua Musyimi
Author: Victoria N. Mutiso
Author: Noeline Nakasujja
Author: David M. Ndetei
Author: Sam Nightingale
Author: Gabriela Novotni
Corporate Author: et al.

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